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Dry skin

Conditions

Pimples

When the sebaceous glands produce too much oil, it can get trapped under the skin, combine with dead skin cells, and clog the pores. When this happens, bacteria can build, and cause inflamed, puss-filled bumps known as pimples, zits, or acne.

Teenagers are prone to pimples because of their overactive hormones during puberty. And women are more likely than men to get pimples because of the hormonal changes that happen during menstruation, and pregnancy. But these unsightly bumps can affect children as young as 10, and adults well into their forties.

There is no single cause for pimples; this skin condition can be the result of many combined factors. Some of these zit-causing reasons include hormones, exposure to oils, stress, using the wrong skincare products, and pressure from wearing helmets or chinstraps. Medications such as those containing lithium, iodides, steroids, and bromides can also contribute to pimples, and worsen existing breakouts.
Herbal Pimple Treatment
Pimple breakouts can range in severity, and since everyone’s skin is different there is no one size fits all method for zapping zits. A combination of lifestyle changes, medications, and natural home remedies can be used to clear existing breakouts and prevent new ones from occurring.

Drug Treatments for Pimples

Over the counter creams, cleansers, and gels that contain benzoyl peroxide and salicylic acid are the most commonly used topical medicines for treating mild breakouts. Salicylic acid is a beta hydroxyl acid that promotes rapid shedding of the skin cells. This acne-fighting ingredient also neutralizes bacteria, and constricts pore diameter to reduce pore blockage. Salicylic acid can cause irritation, dryness, peeling, burning, and stinging of the skin. Using other acne-fighting ingredients with salicylic acid can increase burning.

Benzoyl peroxide is an organic compound that acts as a peeling agent to increase skin turnover, clear pores, and reduce bacteria count. The most common side effect of benzoyl peroxide is irritation, and drying of the skin. After a week of using products that contain benzoyl peroxide, the skin builds a tolerance and the drying, and irritation will usually subside.

Less common side effects of benzoyl peroxide include burning, swelling, itching, and peeling. This acne-fighting ingredient can bleach hair, and clothes, so it should be applied with care. Although creams, gels, and cleansers that contain salicylic acid and benzoyl peroxide are available over the counter, pregnant women, and women who are nursing should consult a doctor before using them on their skin.

Simple Breakouts and Antimicrobials

Unfortunately, severe pimple breakouts are not easy to get rid of with over the counter medicines. These types of breakouts usually require the help of a dermatologist. A dermatologist will evaluate the skin, and determine the best way to heal current breakouts, prevent new ones from forming, and reduce the risk of scarring.

Dermatologists commonly prescribe topical antimicrobials, topical retinoids, or oral antibiotics to treat pimples. These medications can be prescribed alone, or in several combinations to improve their effectiveness.

Topical antimicrobials inhibit the population of the p.acnes bacteria, and promote healing of breakouts. Common types of antimicrobials prescribed by dermatologists include:

Azelaic acid

Azelaic acid occurs naturally in the skin and is used to treat both inflammatory and non-inflammatory acne. Side effects of this drug include dryness, and lighting of the skin.

Clindamycin

Clindamycin is a semi-synthetic antibiotic that treats acne. Side effects of this drug include skin dryness, and irritation. Since clindamycin is a topical antibiotic, there is a chance of bacterial resistance if it is not used as directed.

Erythromycin

Topical erythromycin is an antibiotic that is usually combined with benzoyl peroxide to increase effectiveness. Side effects of this drug include drying of the skin, and irritation. Use erythromycin as directed to reduce the risk of bacterial resistance.

Sodium sulfacetamide

Sulfacetamide is usually used to treat inflammatory acne. This drug opens clogged pores, and kills bacteria. The smell, and grittiness of products containing sulfur is strong, and may not appeal to users.

Benzoyl Peroxide

Although benzoyl peroxide can be found in drug stores, dermatologists may find it necessary to prescribe stronger concentrations of this medicine to treat pimples.

Topical retinoids are a derivative of vitamin A. These retinoids work to unclog pores, and prevent pimples from forming. Commonly prescribed topical retinoids include:

Tazarotene

Tazarotene is a synthetic retinoid that should not be used by pregnant women due to the increased risk of birth defects. Side effects of this medication can include skin irritation.

Adapalene

Adapalene is a synthetic retinoid that acts as an anti-inflammatory. Side effects of this drug include skin irritation, and dryness.

Tretinoin

Tretinoin is a natural retinoid that can effectively unclog pores. This drug is very harsh on the skin. Side effects include dryness, irritation, redness, burning, itching, and scaling. Some of these side effects can be minimized by reducing the amount of medication applied to the skin.

Oral Antibiotics

Oral antibiotics are effective at treating persistent acne. When taken orally, antibiotics reduce the p.acnes population, and reduce inflammation to promote healing of pimples. Antibiotics are not typically prescribed for more than six months; if overused, these drugs can cause resistance to bacteria. Commonly prescribed oral antibiotics include:

Erythromycin

When taken internally, erythromycin can cause irritation of the gastrointestinal tract.

Tetracycline, Doxycycline, and Minocycline

These drugs are effective at reducing inflammatory pimples. Tetracycline, and derivative drugs affect the development of bones and teeth, so they should not be used by children under the age of eight, and pregnant or breastfeeding women. Doxycycline is especially effective at treating inflammatory acne. In addition to skeletal damage in children, doxycycline can cause sun sensitivity.

Sometimes pimples can start deep in the skin, and form cystic acne. Cystic acne is the most difficult type of breakouts to treat. If cystic pimples are not treated properly they can become severely inflamed, rupture, and cause permanent scarring of the skin. In cases such as these, dermatologists may need to administer inter-lesional corticosteroid injections to reduce inflammation and promote healing. Skin doctors can also drain, and extract puss from large cysts to speed healing.

Isotretinoin

Isotretinoin is a man-made retinoid used to treat cystic acne that does not respond to other medications. This drug is taken in pill form up to twice a day for 16 to 20 weeks, and the results can last for years. Isotretinoin is used hesitantly due to the long list of serious side effects. One such side effect includes the possibility of severe birth defects in developing fetuses.
Acne Problems
Women who use isotretinoin should use two forms of birth control for one month before starting the drug, during the entire treatment, and one month after treatments end. Women should not breastfeed while taking isotretinoin, and they should talk to a doctor to get an all clear before getting pregnant after taking the drug.

Other Side effects of Isotretinoin Include:

  • severe chest pain
  • severe abdomen pain
  • blurred vision
  • dizziness
  • severe headaches
  • bone pain
  • joint pain
  • nausea and vomiting
  • rectal bleeding
  • diarrhea
  • depression
  • skin dryness
  • dryness of the eyes
  • dryness of the nose
  • hair loss

These topical retinoids, topical antimicrobials, and oral antibiotics are approved for use in the United States, and may not be regulated for use on pimples in other countries.

Oral contraceptives regulate hormones, and keep oil glands under control, so they may also be prescribed as a way to reduce breakouts in women. Oral contraceptives may not be appropriate for women over the age of 35, those who have blood clotting disorders, and women who smoke.

Natural Remedies for Pimples

Drug treatments are not the only way to manage pimples; natural treatments can also be used for mild cases. Natural treatments may take longer to work, but they are cheaper than medication, and less likely to cause adverse side effects. Here are some home treatments that can be used to banish pimples from the skin.

Tea tree oil “ tea tree oil has antiseptic properties that can reduce acne-causing bacteria and clear acne blemishes. Tea tree oil should not be used at full strength. Instead, mix 5 percent tea tree oil with 95 percent water. You can also purchase premixed ointments from health food stores, or online vendors.

White vinegar and garlic juice mix “ vinegar regulates PH levels in the skin, and garlic has antibacterial and antimicrobial proprieties that kills infections, and helps repair skin. Use a juicer or cheesecloth to extract the juice from two cloves of garlic, and add two tablespoons of vinegar. Use a cotton ball to apply the mixture to affected areas. Let the vinegar, and garlic sit for 20-minutes, and rinse it off with warm water.

Steam facials “ steaming the face three times a week for 15-minutes per session can unclog pores, and release oil, and dirt form the skin.

Oatmeal facial “ oatmeal tones the skin, soothes irritation, and pulls impurities from the pores. Use a blender to crush oatmeal into a fine powder. Add a little warm water to the oatmeal powder, and mix. Apply the oatmeal to the face, let it dry, and then rinse it off with warm water.

Grapefruit seed extract “ grapefruit seed extract has antiviral and antibacterial properties that can kill bacteria, and heal acne. Mix three drops of grapefruit seed extract with one tablespoon of water. Apply the mixture to pimples with a cotton ball.

Lifestyle Changes to Prevent Pimples:

Although there is no single cause of pimples, lifestyle factors can play a role in breakouts. Here are some things you can do to reduce the likelihood of clogged pores, bacteria, and oil buildup.

Keeping Your Face Clean

Wash your face twice a day with a soft washcloth, and a mild cleanser. Avoid using harsh scrubbing sponges on the face because this can cause irritation, and injury to the skin.

Keep your hands out of your face. Popping or picking at pimples can transfer dirt and bacteria, increase inflammation, and worsen breakouts. On those rare occasions when you have to touch your face with your hands, wash them first.

Washing Pillowcases

Keep pillowcases, and sheets washed regularly to keep dirt, bacteria, and oil from building up, and transferring to your face. Wash hair regularly, and don’t use oily products on the hair.

Exercise

Exercise for at least 30-minutes a day. Regular exercise can decrease breakouts by reducing stress, and regulating hormones. Sweating also slows down the production of oil in the glands, and reduces the likelihood of pimples.

Make Up & Cosmetics

Switch to cosmetic products labeled, Noncomodegenic or Oil-Free. These types of cosmetics reduce the likelihood of allergic reactions, and clogged pores.

Use clean makeup sponges to apply makeup. And wash makeup brushes regularly to prevent the transfer of bacteria.

A face full of pimples can cause you to shy away from social situations. But having zits is not the end of the world. With the wide range of medicines and natural treatments available, embarrassing breakouts can be effectively managed.

Conditions

Toe Nail Fungus

When fungi infect a nail, the result can be an infection of nail fungus called onychomycosis. A white or yellow spot appearing under the tip of the nail may be the first sign of a nail fungal infection. The nail may become discolored, thickened and develop brittle crumbling edges as the fungus goes deeper into the nail. The condition is usually not painful and often has no other symptoms, but it is unsightly and can be painful for some people. If the nails become very thick, wearing shoes may be uncomfortable unless you trim down the thickness. However, you must use great care when trimming the thickened nail, because excessive bleeding may occur if you cut into the quick.
What Does Toe Nail Fungus Look Like
When a nail is infected, a condition called onycholysis may also develop, which causes the nail to separate from the nail bed. Onycholysis may cause pain in fingertips or toes and produce a faint odor. Toenail fungus can also cause serious complications for people with diabetes or for people with suppressed immune systems.

Toenail fungus infections are often hard to treat, because it is difficult to reach the infection that embeds itself inside the nail. Nails may clear up for a time after treatment only to have the condition recur later. However, there are various home remedies as well as medications available to treat nail fungus. A complete cure of the condition may take as long as a year and sometimes longer.

Symptoms

  • Nails with distorted shapes
  • Thickened nails
  • Nails with crumbly, ragged or brittle edges
  • Nails with a dull appearance
  • Debris build up under the nails causing them to become discolored or to darken

After a fungal infection gets started in a nail, it will usually remain indefinitely unless it is treated, so begin to treat the condition at the first sign of nail fungus.

Risk Factors

  • Living in a warm climate
  • Working in a damp or humid location
  • Shoes and socks that do not absorb perspiration and that hamper ventilation
  • Walking in damp public shower rooms, gyms and swimming pools without shoes on your feet
  • Heavy perspiration
  • Family history of the condition
  • Older age
  • Being in poor health
  • Having athlete’s foot or psoriasis
  • A weak immune system, poor circulation or diabetes
  • An injured nail, injured skin or an infection

Older people usually have reduced blood circulation, and their nails grow slower and get thicker as they age, causing a greater risk for infection. Men tend to be more prone to toenail fungus than women, especially if they have a family history of the condition.

People with immune systems weakened by AIDS, leukemia, cancer treatments or other medication and those who have diabetes or have had an organ transplant should see a doctor immediately if they have symptoms of nail fungus. These infections can spread to other areas of their bodies and cause serious problems. Diabetics frequently have an impaired nerve supply to their feet because of poor blood circulation and have a greater risk of developing a serious skin infection called cellulitis. Even a seemingly minor injury or nail fungal infection can cause potentially serious consequences for people with diabetes.

Even people who do not have weakened immune systems may experience pain and permanent damage to their nails from fungal infections.

Causes

Molds and yeasts or a group of fungi called dermatophytes can cause nail fungal infections. These fungi are microscopic organisms and can survive without sunlight. The warm, moist environments in showers and swimming pools are ideal places for these microscopic organisms to live, and they can attack your skin even through invisible cuts or a tiny separation between your nail and nail bed.

They typically cause infections only when your exposure to warmth and moisture is continuous. Toenail fungus occurs more frequently than fingernail fungus, because shoes provide a perfect warm, moist environment for fungi to flourish, and the blood does not circulate in the toes as well as it does in the fingers, so your immune system does not fight against the infection as effectively in the toes. People over 60 years old usually have a slightly weakened defense against the invasion of fungi, so they are more prone to develop toenail fungus as they age.

Prevention

It is always better and easier to prevent an infection than to attempt to cure it, so here are a few tips to help prevent toenail fungus:

  • Always use good hygiene, keep nails clean and wash your hands after touching a nail that has infection to prevent spreading it to other nails.
  • Keep nails trimmed short and straight across, and file thick areas of your nails.
  • Dry your toes well after swimming or bathing.
  • Wear synthetic socks to draw moisture away and to help keep your feet dryer than they would be if you wore wool or cotton socks. During cold weather, you can wear wool or cotton socks over the synthetic socks to keep your feet warm. If your feet perspire, change your socks frequently. Remove your shoes periodically, and wear open-toed shoes occasionally.
  • Do not cut or tear the skin around your nails to help prevent germs from invading.
  • Wear shoes or flip-flops in public showers and around pools.
  • Treat your feet and the insides of your shoes with anti-fungal powder or spray.
  • If you get pedicures, either bring your own instruments, or ensure that your nail salon sterilizes their instruments before using them on your toes.
  • Do not trap moisture on your nails by wearing polish or artificial nails.

Tests and Diagnosis

Psoriasis, contact dermatitis, yellow nail syndrome, nail bed tumor and other conditions can appear to be a nail fungal infection, so your doctor will need to scrape some of the debris from under your infected nail and analyze it to identify the cause of your infection. Your doctor can examine the debris under a microscope or culture it in a lab. Yeast and bacteria microorganisms as well as fungi can infect your nails, so your doctor can decide on the best treatment when he or she knows what is causing your infection.

Cures and Remedies

Pharmacutical remedies

Toenail fungus is usually hard to heal, and it often recurs after healing. You can get non-prescription ointments and creams to treat it, but they usually are not very successful in curing the infection.

Prescription Lacquer

If your infection is not severe, your doctor may prescribe ciclopirox, an anti-fungal nail polish called Penlac, for you to apply to your nails and skin every day for about a year. You should apply the polish daily for a week, and then use alcohol to wipe off the layers of Penlac and start the process again, keeping it up for a year. It has been effective in clearing some toenail fungus infections when used as directed, and it is usually more effective when used in combination with topical urea cream. Ciclopiroxolamine and butenafine are also used to treat nail fungus and are effective when used every day for a year or longer.

Topical Medications and Lotions

Your doctor may advise you to use other topical anti-fungal medications, and apply them along with a non-prescription lotion that contains urea, which helps them absorb faster. Your doctor may decrease the amount of infected nail to treat with a process called debridement – filing the surface of your nail. That process may increase the topical medications effectiveness. Topical medications normally do not cure the toenail fungus unless you use them in combination with oral medications.

Oral Medications

Your doctor may recommend an oral anti-fungal medication like terbinafine – Lamisil, or itraconazole, – Sporanox. Studies show that these products are the most effective for treating toenail fungus. When you take these medications for six weeks to three months, you should grow a new nail without infection, taking the place of the infected nail. It may take more than four months to get rid of an infection with these medications, and the infection may return if your feet remain in a warm, moist environment. When you use terbinafine in conjunction with amorolfine nail lacquer, it can be more successful and produce more cost effective results.

Oral medication is frequently recommended for people who experience pain or discomfort due to a nail infection, have diabetes or cellulitis and for those who dislike the appearance of their infected toenails and want an effective treatment for it.

Side Effects

Possible side effects of anti-fungal drugs can be as minor as skin rashes or as severe as liver damage. Consequently, doctors may advise people who have liver disease, congestive heart failure or are taking certain medications not to take anti-fungal drugs.

Surgery

If you have a very painful or acute nail infection, your doctor may recommend surgical removal of your nail. You will probably grow a new nail to take its place, but it may be a year long process for it to completely grow back. After removing the infected nail, your doctor may treat the nail bed with ciclopirox to help prevent recurrence of the infection.

Photodynamic Therapy

Photodynamic therapy involves using a laser to irradiate the nail after treating it with an acid. The laser light source kills fungus in the nail bed. Physicians have been using a Noveon-type laser for some types of cataract surgery, and it is now proving to be quite effective at treating toenail fungus with no pain. Even common laser pointers can aid the appearance and growth of an infected nail when they are pointed close to the nail for a few minutes each week.

Home Remedies

Some people prefer to treat toenail fungus with home remedies because they are less expensive, and the medical treatments are not always effective. These home remedies have no controlled clinical trials to prove their effectiveness, but some people have reported that they helped or cured their nail fungus. As with all toenail fungus treatments, it can take a long time six months to a year for any remedy to work, so do not become discouraged and stop the treatment too quickly. If you are persistent, you may find relief for your condition.
Toe Nail Fungus Natural Remedies

Vinegar

Studies have shown that vinegar hampers the growth of certain bacteria. Experts recommend that you soak your feet in a solution of one part vinegar to two parts warm water for 15 to 20 minutes every day. After soaking, rinse and dry your feet well. If the vinegar soak causes irritation, make the solution weaker, or soak for a shorter time or less frequently.

Vicks VapoRub

People with toenail fungus have reported that applying Vicks VapoRub to the affected area has helped with the condition. Your doctor can advise you about how to use this remedy to gain the most benefit from it.

Hydrogen Peroxide

Some people have reported that applying hydrogen peroxide to infected nails daily helps the condition to some extent. The peroxide helps to control the excessive bleeding that occurs if you trim a nail too closely.

Bleach

You may be able to cure toenail fungus with household bleach diluted in water and applied to the toenail.

Use toenail clippers to trim your nails as short as you can without cutting into the quick. This assures that the bleach will reach more of the fungus. File the toenails down from the top, using care not to go through the nails. There are several different methods for treating toenail fungus with bleach.

  • Mix one part of bleach with ten parts of water and apply to your infected toenails with a cotton swab. Leave the mixture on your toenails, and apply a fresh coat of the solution twice a day.
  • Use a bleach pen to apply bleach to your toenails after bathing, and do not rinse it off.
  • Mix one part of bleach to ten parts of water and soak your feet in the solution for 15 to 20 minutes every day. Thoroughly rinse and dry your feet after soaking.
  • You may soak your feet in the mixture for 30 minutes one time a week if your condition is less severe, or to eliminate the possibility of recurrence after a cure.

Keep soaking your feet for at least three months to be certain that your fungus is completely eliminated. If you do not see improvement in a few months, continue the treatment for at least a year before giving up. If you are not consistent with the treatment and let it lapse, the fungus may get stronger, and you will have to start over.

HERBAL REMEDIES

Some natural ingredients are successful in helping to heal fungus, but they may not work very quickly or be as effective as you would like them to be. However, there have been some very effective products developed recently, and they seem to produce successful results rather quickly. The following products were tested and proved to remove toenail fungus and improve toenail appearance dramatically.

ZetaClear has proved to be effective in treating toenail fungus with all natural ingredients. The product proved to be 100% effective in tests, and most users reported improvement in about two weeks. Their toenails were free of fungus after about three months, but some people kept using the product for a while longer to ensure that the infection would not recur. They reported clear, shiny healthy looking nails after using the product. ZetaClear uses natural oils in its formula and is extremely potent, but it does not cause skin irritation.

Fungisil is another highly effective product and produces the same results as ZetaClear, but it may take about a month longer for some people to eliminate toenail fungus. Fungisils success rate is also 100% and leaves users with healthy nails after treatment.

Another natural treatment for toenail fungus is Nail-Rx by Native Remedies. It has a 90% rate of success and provides excellent results for most users. The fungal infection was completely gone after only three months of use for 80% of those tested.

ALTERNATIVE REMEDIES

The following remedies have no scientific verification, but have been effective in treating toenail fungus for some people.

  • Some people report curing toenail fungus with Australian tea tree oil, but there is no verification of its effectiveness.
  • Some studies show that Thyme oil has the potential to be effective in treating toenail fungus.
  • Some people believe that grapefruit seed extract is a natural antimicrobial, but studies show that the antimicrobial activity in the extract may be due to contamination with synthetic preservatives that were probably not made from grapefruit seeds.

Cost of Treatment

  • The cost of laser treatment can be from $1000 to $2500, and insurance policies usually do not cover the procedure.
  • Oral medication may have a cost of around $1000.
  • Natural remedies can cost from about $100 to $200, and many of them are highly effective.
  • Non-prescription creams and ointments are fairly inexpensive sometimes costing less than $20 – but are usually not very effective.
  • Alternative remedies usually cost less than $50, but there are no studies proving their effectiveness.
  • Home remedies are very economical and usually use products that you already have in your kitchen.

It does not seem to matter whether you use prescription medication, natural products or home remedies to treat toenail fungus it takes at least a minimum of three months to cure, and sometimes the process takes over a year. Depending on the method of treatment you choose, it can also be quite expensive. Whichever remedy you decide to use, be patient and persistent, use good hygiene and common sense and then finally say good-bye to toenail fungus.

Vitamins

Fat Soluble Vitamins

Fat soluble vitamins are stored in the body’s fatty tissue and liver. These vitamins are used over a period of time unlike water soluble vitamins that need to be replenished daily. Individuals with an inability to digest fats, as in intestinal disorders or persons with reduced consumption because of low fat diets, may have deficiencies in fat soluble vitamins, which include A, D, E and K. Excesses occur in the body as fat soluble vitamins are not as readily eliminated.

A healthy well-balanced diet containing foods from all four food groups is the way to ensure the body is obtaining adequate amounts of these vitamins.

Vitamin A

Vitamin A consists of retinols and carotenes (alpha, beta and gamma), which are converted in the body after consuming animal and plant products. The vitamin in carotene form is transformed into retinol while in storage, or into the active form retinal, and back again as needed. Vitamin A conversion takes place in the intestine. Healthy sources of vitamin A include:

  • Animal fats
  • Butter, buttermilk or margarine
  • Cod liver oil or oily fish
  • Egg yolks
  • Green leafy vegetables
  • Liver
  • Yellow/orange fruits and vegetables

Purpose

Vitamin A is essential for fighting infection, maintaining healthy body tissues, and contributes to bone and teeth development. In reproduction, vitamin A in retinal form, binds to the nucleus of cells and assists with beginning and ending gene transcription, making it essential in neonatal development and ongoing growth and repair. Vitamin A, in the form of retinal, binds to the rods and cones of the eye, permitting light adaptation and the ability to see color.
Fat Soluble Vitamins
Vitamin A as retinoic acid is a successful acne treatment as it shrinks sebaceous glands and inhibits secretions. In the form of isotretinoin, vitamin A decreases the number of skin bacteria and the bacterial nutrient sebum.

Recommended Daily Dosages:

  • Infants require 1,300 to 1,650 IU daily depending on age.
  • Children require 1,000 to 2.000 IU daily depending on age.
  • Women require 2,300 IU of vitamin A daily.
  • Men require 3,000 IU of vitamin A daily.

Deficiencies

Getting less than the minimal daily requirements is a concern for children in third world countries. Another form of deficiency occurs in persons who eat low fat diets, conditions that prevent fat absorption, or those subjected to chronic oxidants like cigarette smoke.

Inadequate amounts of vitamin A cause a preventable form of blindness as keratin deposits and builds up on the cornea, causing erosion and destruction. Deficiencies of this vitamin lead to impaired growth and development, inability to fight infection, malfunction of the gastric, urinary, and respiratory systems due to impaired tissue development, night blindness and dry, thickened and peeling skin.

Toxicity

Excessive vitamin A intake results in anorexia, bone and joint pain, changes in mental state, drying and peeling skin and lips, yellow/orange discolored skin, hair loss, vomiting and weakness. Taking vitamin A in amounts exceeding the daily requirement, results in birth defects in unborn children.

Tips: Though vitamin A is not destroyed by cooking, freezing foods could result in a 10-20% loss.

Vitamin D

Whether absorbed and synthesized by the skin or ingested, vitamin D is absorbed by the liver through the blood and transformed into calcidiol. Once converted, vitamin D is transported to the kidneys and the immune system through the blood. In the kidneys, vitamin D is transformed again and recirculated in the blood where it binds to receptor sites throughout the body. The skin only synthesizes the necessary amount of the vitamin, after which it is no longer manufactured, so overdoses cannot occur in this manner.

The vitamin D group contains D2 (calciferol), D3 (7-dehydrocholesterol), D4 (22-dihydroergoasterol) and D5 (dehydrositosterol). Healthy sources of vitamin D include:

  • Butter fat
  • Cod liver oil, salmon, and oily fish
  • Egg yolks
  • Foods that have been irradiated
  • Fortified milk and foods
  • Sunlight

Purpose

In the blood, vitamin D regulates calcium and phosphorus, thus contributing to bone and teeth formation.

Vitamin D also aids in white blood cell production and determination. The vitamin increases infection fighting white cell activity and contributes to the chemical white cells excrete in combating bacteria, fungus and viruses. Some research studies suggest that increasing daily intake to 1000 IU daily has a dramatic effect in preventing cancer.

Because of vitamin D’s wide range of abilities, persons found to have low levels overall had higher mortality rates and premature aging due to body malfunction.

Recommended Daily Dosages

Infants to adults require 200 IU of vitamin D daily. Elderly adults require 400 IU daily.

Deficiencies

Persons getting less than the minimal daily requirements experience irritability, weakness, malabsorption of calcium and phosphorus causing poorly developed or deformed bones and teeth in a condition known as rickets. Adults may experience osteomalacia, where bones thin, become fragile and are accompanied by muscle weakness.

Toxicity

Ingesting excessive amounts of vitamin D results in abnormal kidney function, anorexia, anxiety, excessive urination and thirst, excessive blood calcium levels, nausea, vomiting and weakness.

Tips

15 minutes of exposure to sunlight daily allows the skin to synthesize enough vitamin D for 24 hours. However, vitaimin D deficiencies are still noted in third world countries where there is an abundance of sunshine. Individuals are advised to consume meats or fortified milk and foods to ensure an adequate intake.

Vitamin E

The vitamin E group consists of tocopherols and tocotrienols and each has four forms, alpha, beta, delta and gamma. The human body requires alpha-tocopherols. Vitamin E is absorbed by the liver from the intestine and recirculates it through the bloodstream. Healthy sources of vitamin E include:

  • Asparagus
  • Avocado
  • Eggs
  • Leafy green vegetables
  • Milk
  • Nuts
  • Rice
  • Seeds
  • Vegetable oils
  • Wheat germ
  • Whole grain foods

Tocotrienols are specifically found in barley and other grains, nuts, saw palmetto, wheat germ and vegetable oils.

Purpose

Vitamin E is essential for maintaining healthy cell membranes as it is believed to act as an antioxidant which minimizes aging effects and disease processes brought about by free radicals on the body. Free radicals are molecules with an unpaired electron. These combine with oxygen to cause damaging effects commonly associated with cardiovascular disease and cancer.

Tocotrienols have been researched and show promise in protecting brain cells against damage, inhibiting cancer and decreasing blood cholesterol. The unsaturated chain increases absorption into fatty tissue making it more effective as a protectant.

Vitamin E in the lining of blood vessel walls helps minimize build up of harmful plagues and blood clots. In addition, early research suggests that vitamin E may play a part in preventing age related macular degeneration in the elderly.

Recommended Daily Dosage

  • Infants require 6.75 to 10 IU of vitamin E daily.
  • Children require 9 to 10 IU of vitamin E daily.
  • Adults require 22 IU of vitamin E daily.

Deficiencies

Inadequate amounts of vitamin E result in edema, muscle weakness and neurological deficits related to poor nerve conduction. Anemia occurs as a result of red blood cell damage.

Toxicity

Excessive doses cause breast enlargement, blurred vision, headaches, flu-like symptoms, hemorrhagic strokes and prolonged bleeding times. Administering the vitamin to low birth weight infants may result in colitis and sepsis. Pregnant women are advised against taking vitamin E supplements as they cause congenital heart defects in unborn children.
Benefits of Fat Soluble Vitamins

Vitamin K

The vitamin K group consists of K1 (phyloloquinone) and K2 (menaquinone). Synthetic forms of the vitamin include K3 (menadione) found in pet foods (but banned in OTC use), K4 and K5, which inhibits fungal growth. K2 is naturally manufactured by the bacteria in the large intestine. Vitamin K requires bile salts and fats to be properly absorbed. Healthy food sources include:

  • Avocados
  • Dairy products
  • Eggs
  • Green leafy vegetables
  • Kiwi fruit
  • Meats

Purpose

The vitamin allows the liver to synthesize clotting factors ( II, VII, IX and X), which are vital in preventing bleeding abnormalities. Vitamin K is used as an antidote for coumadin and hemorrhagic rat poisons.

Topically, the vitamin is prescribed to diminish post surgical bruising, broken capillaries, rosacea and dark under eye circles. As infants are not born with the intestinal bacteria necessary to form vitamin K, an injectible form is administered.

There is a correlation between vitamin D and K in the development of healthy teeth and bones. Ongoing research suggests that vitamin K reduces liver and prostate cancers.

Recommended Daily Dosage

  • Newborns receive 0.5 to 1.0 mg injections of vitamin K at birth.
  • Infants require 10 to 20 mcg of vitamin K daily.
  • Children require 15 to 100 mcg of vitamin K daily, depending on age.
  • Women require 90 mcg of vitamin K daily.
  • Men require 120 mcg of vitamin K daily.

Deficiencies

Inadequate amounts of vitamin K result in prolonged bleeding times or hemorrhagic conditions. Individuals with intestinal disease are unable to manufacture vitamin K and are in need of supplementation. Prolonged use of large doses of antibiotics annihilate the bacteria necessary to produce vitamin K.

Toxicity

Vitamin K3 has been banned from OTC supplements as ingestion results in allergic reactions, anemia and destruction of liver cells.

Tips

1 tablespoon of parsley contains 153% of the FDA’s recommended daily allowances of vitamin K.

Resources

WebMd.Com
Cdc.Gov
National Institute of Health

Vitamins

Vitamin D5

Sitocalciferol or Vitamin D5 is one of six different forms of vitamin D, which are numbered from D2 to D7. All six of these forms are based upon calcitrol, and will be converted into calcitrol by the body when they are consumed. They differ in their origin, however, with vitamin D2 and D3 being naturally available. Vitamin D5 is a synthetically produced form of the vitamin.

Vitamin D is a fat-soluble chemical. It is only found naturally in a few types of food, but in some countries including the US, vitamin D is added to other foods such as milk. Stores of vitamin D can be built up in the body. Having too much or too little vitamin D in the body can be harmful.
Benefits of Vitamin D5
Maintaining the optimum levels of this vitamin is very important in order to stay healthy. Vitamin D has a particularly strong effect on the bones. If the body does not get enough vitamin D then the bones can become weak and can grow abnormally. If the level of vitamin D in the body become too high, and reaches toxic concentrations, then the bones can be weakened.

Common Forms

The most common forms of vitamin D are D2 and D3. Vitamin D2 is produced by plants and can therefore be obtained from food. Vitamin D3 is produced in the body. When the skin is exposed to the ultraviolet B or UVB rays in sunlight, the synthesis of vitamin D3 in stimulated in the skin. People can also obtain both D2 and D3 from foods that have been artificially fortified with vitamin D.

Vitamin D5 is an artificially produced analog of vitamin D3. An analog is a chemical that shares some structural properties with another chemical, but which can behave differently from it. Vitamin D5 is structurally similar to vitamin D3, and both can be used by the body in similar ways. The D5 form is less toxic than the D3 analog, however, which makes vitamin D5 a better option for medicinal uses of vitamin D.

The 1α-Hydroxyvitamin D5 form of the vitamin was designed and produced by a team of scientists at the University of Illinois, Chicago and has since been studied in a number of experiments to test its safety and efficacy as a treatment for various cancers, particularly cancers of the breast, prostate and colon.

Chemistry

Vitamin D is a prohormone rather than being a true vitamin. When it is consumed, the body metabolizes it into a number of chemicals that are hormones. Hormones are chemical signals that are used by the body to control various functions.

Vitamin D5 is an analog of vitamin D3. They have very similar structures, but vitamin D5 has been slightly modified. Just a few of the atoms have been changed. Many different analogs of vitamin D3 were designed by scientists searching for a less toxic version of the vitamin that could be used for medicinal purposes without causing problems with toxicity.

Over 1500 of these analogs were produced. The available forms of vitamin D are now classified into six primary forms, named D2, D3, D4, D5, D6 and D7. Each form has a slightly different molecular structure, although they are all still basically the same molecule, and have similar functions in the body. The least toxic of these forms is vitamin D5, which has now undergone a number of experiments to test its efficacy and safety for the prevention and treatment of cancer.

Function

Vitamin D is essential for the maintenance of adequate levels of phosphorus and calcium in the blood. Vitamin D helps the body to absorb calcium from the intestine. Both phosphorous and calcium are required for the development and maintenance of strong bones. Vitamin D may also be able to help to protect the body against high blood pressure, cancer, osteoperosis and certain autoimmune diseases, although the scientific evidence for these functions is less clear-cut that that which shows the importance of vitamin D for the skeleton.

The vitamin D which is obtained from food or which is produced in the skin following stimulation by the sunlight is an inactive chemical. It must be converted through two hydroxylation reactions into its active forms in order to be used. The first reaction occurs in the liver, where the vitamin D is converted into calcidol. Next, the second reaction, which takes place in the kidneys, converts this calcidol into calcitrol.

The most active metabolite of vitamin D is calcitrol. Conversion of vitamin D into calcitrol is regulated according to how much calcium and phosphorus is in the blood, the concentration of calcitrol that is already present in the body, and by the parathyroid hormone. This regulation ensures that the calcitrol levels are maintained at the correct level, as long as there is enough vitamin D available from which to produce more calcitrol when it is needed.

Important Function

The most important function of vitamin D in the body is in the maintenance of calcium and phosphorus levels, and so for ensuring there is proper bone growth and development. There are also some other important functions played by this vitamin in the body. It is involved in the working of the immune system, neuromuscular function, and in reducing inflammation. Vitamin D also plays a role, along with other chemicals, in the modulation of a number of genes that regulate cell division, growth, differentiation and death.

Since most of the vitamin D that is consumed in food, fortified foods and supplements, are in the form of vitamin D2 and D3, these are the most important forms for humans. Vitamin D5, however, may have some important uses, particularly in medicine. Vitamin D5 can also perform similar functions to other versions of the vitamin, when it is consumed.

Deficiency

Vitamin D deficiencies are one of the more common vitamin deficiencies, since the levels of this chemical in food are so low. The chances of suffering a deficiency in vitamin D are related not only to a poor diet, and therefore to poverty, but to certain lifestyle choices and to the climate and latitude at which people live. This is because people do not only obtain vitamin D ready made from their food, but can synthesize it themselves. This synthesis relies on sunlight in order to work, however, therefore exposure to the sun is an important guard against vitamin D deficiencies.

The most well known effect of a deficiency in vitamin D is rickets, which is a condition in which skeletal abnormalities and deformities develop in children. Adults who are not obtaining enough vitamin D can also suffer from weaknesses in their bones, and their muscles may also become weakened. This condition is called osteomalacia. Without a sufficient intake of vitamin D, there will not be enough calcium or phosphate in the blood to ensure that bone mineralization and development occurs properly. This will lead to the bones becoming too thin, weak and brittle. They can also become misshapen and deformed.

Risk Factors

Certain groups of people are at a higher risk of developing a vitamin D deficiency than others. People who are elderly or obese are at an increased risk of vitamin D deficiency, as are infants who have been fed exclusively on breast milk, which contains only low levels of vitamin D, and anyone who has experienced very limited exposure to the sun. Some diseases can also increase the risk of a vitamin D deficiency. These are conditions that affect the absorption of fats, such as cystic fibrosis, or disorders that affect the digestive system, such as Crohn’s disease and inflammatory bowel disease.

A vitamin D deficiency can be treated by increasing the uptake of vitamin D through dietary supplements, or, if possible, increasing exposure to sunlight.

Toxicity

An excess of vitamin D in the body can be toxic, but D5 is the least toxic form of this vitamin. It is therefore the most suitable for medicinal uses, since it is less likely to cause adverse side effects than the other types of vitamin D. If vitamin D, in any form, does build up to toxic levels, however, it can be very harmful.

Vitamin D toxicity can result in a condition called hypocalcaemia that can lead to bone loss. In the most serious cases of hypocalcaemia, the damage can be very serious and may even lead to life threatening side effects. The earliest symptoms of toxicity may include nausea and vomiting. Anorexia, which presents as a loss of weight and appetite may also occur. This can be followed by excess thirst and urination, fatigue, weakness, headache, a metallic taste, dry mouth, tinnitus or ringing ears, vertigo and unsteadiness. The functioning of the kidneys can be impaired, and calcium may be deposited in them and around the organs of the rest of the body. This deposition is known as metastatic calcification.

Hypercalcaemia is treated by stopping further intake of calcium or vitamin D, and gradually reducing the calcium levels in the body. This must be done under medical supervision, in order to ensure that the calcium levels can be monitored. In some cases, it may also be necessary for the condition to be treated with corticosteroids and acidification of the urine.

Medicinal Uses

Research into the potential of vitamin D for the prevention and treatment of cancer was stimulated by epidemiological studies that showed people who had high levels of vitamin D in their diet, or who had high levels of sunlight-induced formation of vitamin D in their skins, were less likely to develop cancer. An epidemiological study is one that looks at what is happening in real populations of people rather than setting up an experiment or testing a particular treatment.

Vitamin D5 Deficiency

In studies that were conducted in vitro, that is in isolated cells in a laboratory, Vitamin D3 was found to be effective at preventing cancer. However, there was the problem of toxicity.

The doses that were high enough to reduce the chances of a cell developing cancer were also so high that they would be toxic to patients. This meant that vitamin D3 treatment for the prevention of cancer was not possible. In order to be effective, vitamin D3 treatment would require doses that were hundreds of times greater than those that are normal in the body.

The use of vitamin D as a treatment was limited by the toxic effects that it can have when it is present at high concentrations in the body. In order to test the efficacy of vitamin D against cancer, and to have a prospect of using it as a safe treatment if it was found to be effective, it was first necessary to find a safer alternative form of vitamin D, one which would not have the same toxic effects as vitamins D2 and D3.

Studies of Usage

Vitamin D5 was developed as a possible safe analog of the vitamin for medical use. It is a low calcemic analog of vitamin D. D5 is, in fact, the least toxic form of this vitamin and therefore the safest for medicinal use. A number of studies have been carried out to examine the possible therapeutic uses of the D5 form of vitamin D. Despite the research that has been conducted, vitamin D5 is not yet being used by doctors. Further research is necessary before it can be determined whether vitamin D5 is a suitable treatment.

It is the differences between vitamin D5 and the more common forms of the vitamin, D2 and D3 that make D5 a suitable candidate for clinical trials. The reactions which these different forms undergo in the body have different consequences that make D2 and D3 unsuitable for therapeutic use against cancer. The products of the reactions that take place when vitamins D2 and D3 enter the body are hypercalcemic.

Raising Levels of Calcium

This means that they are very effective at raising the levels of calcium in the blood serum, and D2 and D3 are therefore not a suitable medication for cancer prevention or treatment. They are very effective at playing their role in maintaining the appropriate levels of calcium in the body, as long as they are only present in low concentrations. Vitamin D5, however, can exist in the body at much higher concentrations without causing any problems with toxicity.

Studies have been carried out that have looked at both the therapeutic and preventative potentials of vitamin D5. Trials have been conducted in animals to determine whether vitamin D5 can affect the growth of cancer cells, or prevent animals from developing cancers.

D5 has been found to be effective in both of these types of animal-based study. Work has also been begun which will lead to studies of vitamin D5 in humans. The initial studies have been carried out to determine the doses that should be used in future clinical trials in order to avoid toxicity and adverse reactions. These studies investigated the toxicity of vitamin D5 in animals.

Cancer

The scientific evidence points towards an influence of vitamin D on the risk of developing cancer. It appears to be particularly effective in the prevention of colon cancer, and to have some effect in the prevention of breast and prostate cancer. Results from studies of other types of cancer have been more variable and inconclusive. There is as yet no definitive scientific proof that vitamin D can be effective as a treatment against cancer, or that a high vitamin D intake can help to reduce the risks of developing cancer. Further research is required in order to determine the efficacy of vitamin D against cancer.

Sources

Vitamin D2 and D3 are the most common forms of vitamin D in nature. Vitamin D is still a rare vitamin, even in these forms, and it is only found at low levels in food. The vitamin D that is found in plants is in the form of vitamin D2, while some vitamin D3 can be obtained from certain animal-based products.

The best sources of vitamin D are fish and fish liver oil. Cheese, egg yolks and beef liver also contain some vitamin D3. All of these food sources contain the vitamin in its D3 form.

Vitamin D2 can be obtained at fairly high levels from some mushrooms. The amount of vitamin D2 that is available in mushrooms can be increased by growing them under an ultraviolet light.

Other Ways to Get Vitamin D

Vitamin D does not have to be obtained from food. It can also be manufactured in the skin, and this is the method through which most people obtain a sufficient amount of vitamin D to remain healthy. Anyone who does not get enough exposure to sunlight, either through remaining indoors or living in a part of the world that does not receive enough sunshine, is at risk of a vitamin D deficiency.

For example, the region that is north of the line of 42 degrees of latitude will not be receiving enough sunlight during the winter months, between November and February to produce adequate amounts of vitamin D during these months.

Exposure

The amount of sun exposure that is necessary is fairly low. Although there is no consensus on the amount of time that needs to be spent in the sun to ensure sufficient production of vitamin D, it is probably enough in most climates to spend between 5 and 30 minutes out of doors between the hours of 10 am and 3 pm, with the face, legs, arms or back exposed to the light, twice a week. Excessive exposure to the sun should be avoided, since it can lead to sunburn and an increased risk of skin cancer.

A vitamin D deficiency can be avoided or treated by increasing the amount of vitamin D that is consumed in food, increasing exposure to sunlight, or by taking vitamin D supplements. A traditional treatment for a deficiency of vitamin D was to take cod liver oil, since this is a rich source of vitamin D3.

Supplements

Vitamin D5 is not a naturally occurring form of vitamin D. It can be artificially produced, however, and it was designed as a safer form of the vitamin for medicinal use. Vitamin D5 or sitocalciferol is manufactured from the chemical 7-Dehydrositosterol.

Both the D2 and D3 forms of the vitamin are available in dietary supplements and as fortified foods, although D3 is the most commonly used form. Vitamin D2 and D3 supplements are available in different forms including tablets and injections. Different strengths are available to treat severe deficiencies and to provide an additional source of vitamin D for long term supplementation in people who are at risk of developing a deficiency.

Food Products

In addition to naturally occurring vitamin D, some food products are artificially enriched with vitamin D in order to ensure that people are getting enough of this scarce vitamin in their diets. Food that has been fortified with vitamin D is available in the US and in numerous other countries. Most milk that is sold in the US has been fortified with vitamin D.
Vitamin D5 Supplements
A cup of fortified milk contains 100 IU (International Units) of vitamin D per cup. This is equivalent to 50% of the adequate daily intake of vitamin D for people who are between 14 and 50 years of age. Other dairy products such as cheese or ice cream are not usually fortified.

Other products that may be fortified with vitamin D in the US are breakfast cereals, cereal flours, margarine, orange juice and yogurt. The amount of vitamin D that can be added to a food product is legally restricted in order to prevent anyone suffering from toxic levels of the vitamin.

Most people do not need to take vitamin D supplements, but those who are at an elevated risk of a vitamin D deficiency may benefit from a dietary supplement of the vitamin. People who are elderly, and women who are pregnant or breastfeeding, should consider taking vitamin D supplements.

A dose of 10 micrograms per day is recommended by the UK Food Standards Agency. People who are in one of the other risk groups may also benefit from vitamin D supplementation.

Sources

Mayo clinic: Vitamin D

The Merck Manuals: Vitamin D

National institute of health, office of dietary supplements: Dietary Supplement Fact Sheet, Vitamin D

Food standards agency: Vitamin D

Patient UK: Vitamin D Deficiency

IITRI: Vitamin D5 Ready for Clinical Trials in Breast Cancer

University of Illinois at Chicago medical center, this week, April 5 1999: US Defense Department OKs UIC Vitamin D5 study

International journal of cancer 108: 6: 922-929, 2003: Punj, Graves and Mehta, Cancer Diagnosis and Therapy

Journal of the national cancer institute, 89:3:211-218, 1997: Mehta, Moriarty, Mehta, Penmasta, Lazzaro, Constantinous and Guo, Prevention of Preneoplastic Mammary Lesion Development by a Novel Vitamin D Analogue, 1 alpha-Hydroxyvitamin D5

Journal of steroid biochemistry and molecular biology, 97: 1-2:129-136, 2005: Murillo and Rajendra, Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5

United States PAtent number 6900191: 1 alpha-hydroxyvitamin D5, its synthesis and use in cancer prevention

Herbs

Konjac

Konjac is a perennial plant of the genus Amorphophallus that grows in tropical and subtropical regions of eastern Asia, from Indonesia to India, Japan and China. It is known primarily for its starchy corm, a tuber-like structure that is actually part of the plants stem, but which grows underground and acts as a storage organ for the plant.

Konjac is also known as elephant yam, presumably for the resemblance of its corm to that of the true yam, but the plants are not closely related. Other colloquial names for Konjac are konjaku, devils tongue, snake palm and voodoo lily.

Konjac is primarily used as a source of glucomannan, a dietary fiber that makes up about 40% of the plants corm. Glucomannan is used as a food additive for its thickening and emulsifying properties, and as a nutritional supplement for the treatment of obesity, constipation, high cholesterol, diabetes and acne. It provides a rich source of soluble fiber, considered to be of general benefit to the digestive system, while containing almost no calories.
Konjac Benefits

Where it Come From

Konjac is cultivated in China, India, Japan and Korea. In nature, the plant grows best in tropical or subtropical conditions that provide moderate rainfall and a soil structure that combines a somewhat sandy top layer with a lower layer of mud that can retain water. In Japan and China, it is often cultivated in hilly terrain that is not conducive to traditional agriculture, and each plant requires very little room to get started.

Plants are typically transplanted and more widely spaced in their second and third years, at which time they reach maximum levels of glucomannan content. They are then dug out of the ground for cleaning and processing.

Processing

Traditional processing after the harvest is a very labor intensive operation. The corms are separated from the rest of the plant and washed and peeled by hand before being sliced and dried in the sun. Modern processing incorporates machinery and accelerates the drying process with air heated by burning coal. Regardless of the process used, the goal is to produce a product that is dry enough to be stored and to achieve greater concentrations of glucomannan.

The extent to which konjac is processed depends on whether its intended use is as a food, food additive or nutritional supplement.

Konjac flour is made by grinding the dry corms and separating the lighter components from the heavier flour. What is left contains approximately 70% glucomannan, and is suitable for use in noodles and other dishes. The flour can be further processed to achieve 80% glucomannan content, yielding konjac jelly or gum for use as a thickener or gelling agent, or purified as part of a final stage that produces the soluble fiber used as a nutritional supplement.

History and Origin

Konjac is regularly mentioned in historical Chinese treatises and histories, both as a medicine and, particularly in times of famine, as a food. The earliest known use of konjac as a medicinal herb dates back to the Han Dynasty in China, some two thousand years ago, where it was recommended as a treatment for asthma, infection, cough and skin disorders. Its use continued through subsequent dynasties and has been essentially uninterrupted through the present day.

Konjac, in both flour and jelly form, has a long culinary history in China and Japan. In Chinas Sichuan province, the jelly is used as a tofu substitute and called konjac tofu.In Japan, where it is called konyaku konjac flour is mixed with water and limewater and boiled. Once it solidifies, it can be cut into various shapes. Cut into thin wafers, it can take the place of tofu or thinly sliced raw fish. It is perhaps best known, however, when cut into strips and takes the place of noodles in several stew-like dishes, where it is appreciated for its unique texture. Konjac itself has little or no taste.

Western interest in konjac and glucomannan has grown over the past two decades as the health benefits of dietary fiber have become better understood. Research has focused on its potential for controlling cholesterol and blood glucose, as an aid to losing weight and as a general benefit to digestive health. Results of those studies have been promising. The broader therapeutic claims of traditional Chinese medicine have not been subjected to the same scrutiny and remain unproven.

Uses and Benefits of Konjac

Today, konjac is used for two distinct but related purposes: losing weight and supplementing dietary fiber. Both uses find support in the medical literature, but konjac has also been the subject of unproven claims that have resulted in government intervention.

Weight Loss

The efficacy of konjac for weight loss relies on its ability to absorb up to twenty times its own weight in water. The glucomannan expands after ingestion, and this tends to promote a feeling of fullness as it travels through the digestive tract. To achieve this result, konjac is generally taken with water before meals. An alternative, if less popular, approach is to sprinkle granules of glucomannan directly on food.

Recommended doses for weight loss purposes range from one to four grams of glucomannan taken with eight ounces of water one hour before each meal.

Fiber Supplementation

The American Dietary Association recommends that adults should consume at least 20 to 35 grams of fiber each day. The typical American diet provides between 12 and 18 grams. While oat bran, at 14% soluble fiber content, offers the most concentrated sources of soluble fiber among those catalogued by the ADA, glucomannan comprises at least 40% of konjac by dry weight, making konjac the richest source of soluble fiber in nature.

Clinical studies specific to glucomannan supplementation have shown positive results in the treatment of a number of conditions, including:

Constipation

Soluble fiber absorbs water, softens digestive contents and increases stool volume.

Hyperglycemia and Hypoglycemia

Glucomannan attracts water in the digestive system and becomes a gel, slowing digestive processes and trapping carbohydrates so that blood sugar levels are stabilized.

Diabetes

One benefit of the ability to regulate blood sugar levels is seen in Type 2 Diabetes, where glucomannan has shown potential to reduce blood glucose, insulin and serum lipid levels after meals, an effect that seems to be enhanced by glucomannans relatively high viscosity compared to other soluble fibers.

High Cholesterol

By attaching itself to bile acids in the digestive system and moving them out of the body, glucomannan supplements can help lower cholesterol and reduce the amount of fat present in the blood.

High Blood Pressure

As a corollary to glucomannans beneficial effect on cholesterol levels, one study has demonstrated a decrease in systolic blood pressure in healthy men after a four week course of glucomannan supplements.
Using Konjac
While all of the above benefits are supported by medical research on human test subjects, the clinical studies themselves have uniformly involved relatively small groups of people and short periods of time. It is unclear, then, if the beneficial effects of konjac supplements can be counted on to persist over the long term.

In addition, some studies, even those not looking specifically at glucomannan as a weight loss product, have limited their subjects to people who are obese, making it unclear if konjacs benefits extend to people who are not overweight.

However, soluble fiber in general has been studied extensively, with a great deal of attention to the fact that it produces short-chain fatty acids as it is digested. These acids, in turn, provide a number of health benefits, including:

  • Decreasing synthesis of cholesterol by the liver
  • Regulation of insulin release by the pancreas
  • Regulation of glucose absorption by affecting glucose transporters in the intestinal mucosa
  • Discouraging the formation of polyps by raising the acidity level of the colon
  • Enhancing the absorption of minerals, especially calcium, in the digestive system
  • Increasing the production of a variety of cells and antibodies involved in the immune system
  • Decreasing the ability of irritants to adhere to the mucosal layer of the colon

Konjac has itself been claimed to be something of an antidote to food poisoning. This claim originates from a single laboratory study in which 18 different food products were subjected to exposure to bacteria, including E. Coli and Salmonella, which were allowed to bind themselves to the products.

When the levels of bound bacteria were measured, the largest quantity were bound by sesame seed extract and konjac gum, leading to the tentative conclusion that konjac may help to prevent bacteria from entering host cells. This claim awaits further confirmation, as the effect has not been studied in a clinical setting to date.

Unproven Claims

A number of companies have been sanctioned for making false or misleading claims about the benefits of konjac and glucomannan. The sanctions have generally resulted from the companies exaggeration of the benefits conferred by konjac, from false claims of research support for those exaggerated benefits and from the use of expert endorsers whose expertise and qualifications are similarly exaggerated.

A typical example involves two products called FiberThin and Propolene, which were advertised via infomercials that claimed they would cause rapid and substantial weight loss without any need to exercise and regardless of what the consumer ate. The Federal Trade Commission required the companies involved to pay $1.5 million in settlement of the claims. They were also barred from making unsubstantiated claims for dietary supplements and from misrepresenting scientific studies in their marketing.

A different unproven claim may have its origin in the recommendations found in ancient Chinese herbal texts that list konjac as a treatment for acne and other skin conditions. Today, konjac can be found in several cosmetics and beauty treatments, which typically characterize it as a component that increases the effectiveness of other ingredients. There does not appear to be any research, pro or con, involving these claims.

Side Effects and Cautions

Konjac is not known to have undesirable side effects when used in food preparation or when taken as directed as a nutritional supplement, and its negligible calorie content make it particularly suitable as an aid to weight loss.

This is not to say that it is absolutely safe. Dangers associated with glucomannan stem from its ability to increase in volume by absorbing large quantities of water. These dangers have led to government intervention of two varieties:

Warnings

Products containing glucomannan have been required to include information warning consumers of dangers if the product is not consumed as instructed. For example, Health Canada issued a warning in 2010 that glucomannan in tablet, capsule or powder form should always be taken with at least eight ounces of water and that it should be entirely avoided immediately before bed. Products containing glucomannan are required to carry those instructions and to note the risk of choking and/or blockage of the throat, esophagus or intestine if the product is taken without sufficient liquid.

Bans

In 2001, several deaths and near-deaths of children and the elderly from suffocation while eating a certain type of konjac fruit jelly candy were reported in California. Unlike jellies that melt on contact with saliva, konjac jellies require chewing and, if unchewed, can be inadvertently sucked into the throat. As the jelly expands, breathing can be cut off. The Food and Drug Administration banned sale of the candies in the United States in 2001, a ban followed soon thereafter by the European Union, Canada and Australia. The candies are still available in parts of Asia, but are sold with warning labels and manufactured in larger sizes and in formulations that dissolve more easily.

Dosage, Administration and Cost

As a nutritional supplement, konjac is available in tablet, capsule and powder form. Dosage consists of the equivalent of 500 to 1500 milligrams taken before meals with at plenty of water. If using the powder, it should be stirred briskly in water and it is important to drink the solution before it has a chance to gel.

Konjac can be readily found online or at retail drugstores and nutrition stores like GNC. It is most commonly sold in capsules containing approximately 700 milligrams of glucomannan. Prices are extremely variable, ranging from under $3.00 to almost $20.00 for 100 capsules. Konjac powder can be a cost-effective alternative, but with similar pricing variability. At the extremes, a 500 gram bag of powder can be purchased for $18.00, while buying 500 grams in 100 gram bottles can cost at least five times as much.

Konjac is also found in multi-ingredient supplements, where it is frequently combined with other fiber sources or with ingredients claimed to be effective in losing weight.

Additional Availability

Konjac is also available as a food product, most often as noodles in a variety of shapes and sizes. Some brands have added flavoring, as konjac imparts little or no flavor on its own. Prepared noodles can be found online or at Asian grocery stores and are typically sold packed in water in plastic bags. They can be stored at room temperature and have a shelf life of approximately one year.

For the truly determined, konjac powder can be mixed with water and pickling lime in order to make konjac noodles from scratch. The mixture is boiled for three minutes and allowed to cool. Once cooled, it forms a stable, non-reversible gel which can then be cut into whatever shape is desired.

Conditions

Gout

Alternative names

  • Hyperuricemia
  • Asymptomatic Gout
  • Acute Gout or Gouty Arthritis
  • Interval and Intercritical Gout
  • Chronic Tophaccous Gout

Symptoms

Gout.

There are two different types of gout, primary gout and secondary gout. Primary gout is inherited, which consists of the over production of the uric acid in the blood, a decrease of uric acid in the urine, or both.

Secondary gout occurs when the medication causes the increase of uric acid in the blood. Diuretics can cause this. Kidney failure or the increased destruction of cells, such as cancer patients going through chemotherapy, are also attributed to secondary gout.

You will have redness of the joint accompanied by stiffness, inflammation, and extreme pain. Many will suffer from podagra, a condition where gout forms in the big toe, but you can also contract gout in other joints such as ankles, wrist, fingers, or elbows. 75 percent of first attacks start in the big toe.Gout Remedies

Any type of pressure on the affected area hurts. Something as light as a bed sheet or your sock can cause extreme pain. Gout attacks can get better within a few days, even without treatment.

Four Stages With Different Symptoms:

  • Asymptomatic (without symptoms) Hyperuricemia are elevated levels of uric acid in the blood with no symptoms.
  • Acute Gout or Gouty Arthritis is when deposits of uric acid crystals form in the joint spaces. Sudden onsets of pain will follow, along with swelling, heat, and tenderness.
  • Interval or Intercritical Gout is the period in between attacks where there are no symptoms.
  • Chronic Tophaccous Gout is the most severe and disabling of all stages of gout. It develops over years, causing permanent damage to any of the joints that are affected, and in some cases, the kidneys.

Causes

If there an increased production in uric acid and your kidneys are doing what they need to do to eliminate the acid, it will build up in the blood, a condition called Hyperuricemia. The uric acid forms tiny crystals the size of the point on a needle in the joints or soft tissue. The crystals can also form into kidney stones.

Risk factors

  • Genetics makes up about 20% of all people who suffer from gout.
  • Gender and Age: Gout is more common in adult men between the ages of 40 and 50, with a peak age of 75,
    are more likely to contract gout than woman, children, and young adults.
  • Weight: Being overweight increases the risk contracting gout. The more you weigh, the more frequent the attacks. Having the extra weight makes it harder for the body to do its job. Losing the weight gradually willbe a benefit to those who have high levels of uric acid, even though being on a diet can trigger an attack.
  • Alcohol: People that drink too much alcohol can contract gout as well. The more alcohol you drink, the more the blood is not able to remove the uric acid, the rest crystallizes. Gout attacks happen because the major consumption of alcohol impairs the kidney function.
  • Lead: Some studies have concluded that there’s a strong connection between gout and lead poisoning.
  • Other risk factors that can cause gout are certain foods such as anchovies, asparagus, beef kidneys, dried bean or peas, game meats, gravy, liver. There are so many others, but these are definitely the foods that gout sufferers should watch out for.
  • The kidneys that possess an inability to eliminate waste products.
  • People that suffer from high blood pressure.
  • People who have had organ transplants.
  • Hypothyroidism, or under active thyroid.

Prevention tips

  • Medications: Non steroid anti-inflammatory drugs, or NSAIDs, help with the pain and inflammation, oral
  • Colchicine in small does to prevent future attacks. Zyloprim and Benemid are medications that are used for the treatment of Hyperuricemia.
  • Zyloprim can help in the management of uric acid, but it won’t stop an acute attack of gout that is already present. It can, however, reduce your symptoms when taken over the course of several months.
  • People that use medication for high blood pressure and high blood triglycerides find that these meds can be used for the treatment of gout. Cozaar, a high blood pressure medication, and Tricor, a triglyceride lowering medication, are the two that have been found to help aid in the treatment of this condition.
  • Lifestyle Changes: Controlling your weight keeps the body from having to work harder break down the bodily waste.
  • Drinking large amounts of water removes uric acid from the body.
  • Avoid diets that have a low-carbohydrate intake. When you’re not taking in a substantial amount of carbohydrates, the body can’t burn fat completely.
  • Eating foods that are purine free is key to reducing the frequency of gout attacks. Purine free means that foods that don’t have a nucleus such as an egg. The yolk is the nucleus. They can’t be avoided completely because purines are released when the body recycles dead cells. These foods are egg whites milk and milk products like cottage cheese mozzarell and whey protein, and pulp-free fruit juices.
  • When you have an attack, it is important to avoid excessive exercise, don’t starve yourself, and don’t reduce you calorie intake. The body will continue to break down body tissue and not getting the proper intake of calories per day, the body will compensate by accelerating the breaking down process.

Test and diagnosis considerations

To confirm a diagnosis, a doctor will inject a needle into the inflamed joint and pull a sample of the liquid that lubricates the joint called synovial fluid to analyze. If there are uric acid crystal found in the joint spaces, then you have gout. X-rays don’t work in the early stages of gout, only when the disease is in its later stage, will you see parts of the joint that have been worn away or eroded.
Treat Gout Naturally
Patients will often seek medical attention thinking that finding the gout in its early stages will prevent it from getting worse later. Sometimes symptoms of gout can be confused with another form of arthritis. One form is called pseudogout. It resembles all the symptoms of gout, but instead of having uric acid crystals that form in the joint spaces, it calcium phosphate. In this case, pseudogout.

Treatment options

1. Home treatments

  • Warming the joints with a foot bath and heating pad can help relieve joint pain.
  • Increasing the amount of water that you drink will increase your urination, which decreases the amount of
    uric acid in your blood. According to the Institute of Medicine, men should drink approximately 13 cups of
    water per day, women should drink approximately nine cups, whether it’s in food or drink.
  • NSAIDs, with the help of other prescribed drugs, are used to treat gout. Aspirin should not be taken
    because it can aggravate the condition.
  • Corticosteroids can relieve pain and inflammation of gout in the joint by injecting it right into the joint if
    the pain medication that you have at home doesn’t work.
  • Doctors have been advising patients who suffer from gout to take Vitamin E, B-complex, and folic acid to
    replenish the body’s supply.

This should be done under supervision of a physician, but a solution of half of a teaspoon of baking soda dissolved into a glass of water on an empty stomach. If the stomach is full, the combination of the stomach acid and the water/baking soda solution will turn the water into carbon dioxide gas.

The gas will increase stomach pressure, causing injury. Do not exceed more than seven 1/2 teaspoons or three 1/2 teaspoons if you’re over 60, in a 24 hour period. Don’t exceed the maximum dosage for more than two weeks.

Herbal Remedies

In folk medicine, eating or drinking cherries in various forms has shown to reduce the inflammation caused by gout. They have been promoted to the preventing or treating of the condition.

Other herbal remedies that people tend to use instead of conventional medicine are things like celery seed
oil, cherries or cherry extract, turmeric, artichoke extract, garlic, and various Chinese herbs.

Some people have found that swallowing a teaspoon of celery seed oil gives relief for people suffering from gout. It has been used as a herbal remedy to help with conditions where inflammation is a symptom and rheumatism. Turmeric is known in many countries for its health benefits. In Pakistan, it is used as an anti-inflammatory.

The herbal remedy Flamasil, which is turmeric based, it helps with the degeneration of cells, which is 70 percent of all uric acid production, enhances liver and kidney function, and blocks the enzyme that produces uric acid. With any home remedy or experimental drug, there will be opinions and criticisms about how well or if it works.

Side Effects

The side effects of oral colchicine is usually nausea, vomiting, abdominal cramps, or diarrhea. These side effects make it difficult for the patient to continue using the drug. Corticosteroids cannot be used for every attack you have. If used over time, it can cause deterioration of the joints. It can also decrease the ability for the body to fight off infection and may make these infections harder to treat. You might also notice an increase or decrease in appetite, nervousness, restlessness, problems sleeping, and indigestion.

If you’re using a corticosteroid, via inhalant, you’re more likely to suffer from dry throat as well as headaches, nausea, bruising and/or thinning of the skin, unpleasant sense of taste. Nasal sprays can also irritate the throat, and ointments or gels can cause skin irritation.

Probenicid, or Benemid, is not a good medication to treat acute gout attacks. They can aggravate the inflammation if used in the beginning stages of the attack. It can also cause kidney issues such as renal colic and increased levels of uric acid that can turn into uric acid stones, or kidney stones. Zyloprim side effects are included, but not limited to, an acute attack of gout, nausea, diarrhea, and certain skin reactions such as a rash.

All gout medications have side effects that range from nausea to stomach cramps. Although, there are new medications being developed in clinical trials that will substantially increase the elimination of uric acid and the lowering of uric acid in the blood stream. Researchers are also working on medications that will stop chemical messages that are causing the gout inflammation.

Chinese Research

In China, researchers have invented a medicine that compliments, the Weicao Capsule, that helps relieve gout, therapeutically. This is still in its trial phase, but it has been shown in a study that the capsule has increased urination, which lowers high levels of uric acid and improves kidney function.

Gout can become extremely serious if not treated in it’s earliest stages. There are some people that will dismiss the condition, but gout is very serious and has the capability of interfering with the simplest of everyday things.

Resources

National Institute of Health
Cdc.Gov
MedicineNet.Com

Herbs

Wormwood

Wormwood (Artemisia absinthium)

The benefits of the Wormwood have long been documented and has several benefits and remedies known to man. The following is an in depth look at the constitution and value of the herb and the most beneficial ways to make use of it.

History & Origin

The herb known as Wormwood comes from the plant family of Compositae, genus Artemisia and the specific species absinthium. The genus Artemisia contains over 180 species, making Wormwood quite the herb to be reckoned with out of all other species classification.

It is naturally grows in the more temperate clime zones such as Europe, North Africa and Asia, however more recently it is being grown in North America due to a higher demand (mainly due to the growing interest of holistic medicine).
How to Use Wormwood
The name Wormwood has several origins and is mostly referred to for its bitter taste. The Romans referred to it as “Absinthium” that is derived from the Latin word “absinthial” roughly translated to “bitter”. It’s not exactly sure where the word Wormwood was directly derived, however it has been speculated that it may come from the Anglo-saxon word “wermode” that comes to be translated as “waremode” or also “mind preserver”.

Greek Influence

The Greeks, thinking the bitter quality of Wormwood to be undrinkable, called it “absinthion” and yet they honored the goddess Artemisia (Goddess of the Hunt) with a form of the concentrated substance. It was most typically used over 3500 years ago to help in the expulsion of intestinal worms–hence the name WORMwood.

The highly noted Greek physician Hippocrates would prescribe it to women for the menstrual pains and to combat common occurrence of anemia, jaundice and rheumatism.

As far back as the 16th century, Wormwood has been used for many classic remedies, including the ailments it remedies today. However, the remedies it was meant to help with back in the 16th century may be something scoffed at or frowned upon in today’s modern medicine world.

Wormwood was thought to counteract most of the poisonous effects of hemlock and toadstools. If ever bitten by a sea dragon, Wormwood was a source of comfort to the victim. However, it is still used as a common remedy to help heal open wounds.

Mexican Influence

In Mexican culture, it was customary during their festival to honor the Goddess of Salt to have the women wear head garlands entwined with Wormwood while they ceremoniously danced together.

An old folklore that is sometimes still practiced, is to mix Wormwood with marjoram, thyme, virgin honey and vinegar before you go to bed on St. Luke’s Day and anoint yourself with it to dream of your true partner “that is to be”. It will only work, however if you repeat the following chant three times:

“St. Luke, St. Luke, be kind to me,
In dreams let me my true-love see.”

Wormwood was also intentionally used in large scale brewery’s instead of hops, before the FDA deemed it “unsafe” for consumption, because it resisted putrefaction.

Potential Early Health Issues

Pregnant women should not take wormwood as it is a uterine stimulant & could cause complications including abortion. Children should not be given wormwood, which also means nursing mothers should not take it.

During the prohibition, about the same time that Wormwood was being used in brewery, it has been said that the key ingredient, absinthin, was known to cause brain damage and even death, which resulted in it being banned in the 20th century–this was later found to be a myth (although large amounts of distilled absinthe can cause severe side effects) and wild conspiracy thought of by the Prohibitionists and the wine industry.

Popular Variations & Common Uses:

Besides being a common ingredient for brewing beer and distilling alcohol, Wormwood has most famously lent it’s uses to the French spirit Absinthe, but because of the extremely dangerous oil absinthol that the it contains it has been banned in most countries (including the U.S.). The oil absinthol and the active ingredient thujone has been proven to contribute to nerve depression, severe mental impairment and even the loss of all reproductive function if used over a long period of time.

Wormwood flavoring can also be found in the German drink Vermouth and is also commonly used in the flavoring of food today, however it is used in much smaller quantities and is ever hardly concentrated.
An alternative use for Wormwood comes in the form of commercial and residential landscaping. The towering three to four foot herb is a favored filling technique for professional landscapers and the yellow blooms that the herb produces in the summer time is a bonus when looking for that extra pop of color.

General Benefits

In terms of general benefits of the herb Wormwood, it has been proven to help with many things, however it is mainly used in the holistic aspect of medicinal use. It is most commonly consumed either as a hot tea or a tincture to be taken before meals and is favorably used for:

  • Stimulating the digestive tract and gallbladder function
  • Effective trigger of producing excessive amounts of bile which aids in the function of the gallbladder
  • Typically mixed with peppermint and/or caraway (in a tea) to aid in the calming of heartburn and IBS (Irritable Bowel Syndrome)
  • Expelling of intestinal worms
  • Stimulate feminine menstruation.
  • Stimulates cerebral hemispheres and directly stimulates the cortex cerebri which may aid in nervous diseases like neurasthenia
  • Common muscle relaxant
  • May help to quicken the process of childbirth and help with the expulsion of the afterbirth (it is not recommended however due to the toxicity of the herb)
  • Known to treat anxieties by being used a mild sedative
  • Stimulates poor circulation and aids in the relief of painful rheumatic joints by using the leaves a compress
  • Stimulates/remedies a poor appetite

Wormwood has become a highly popularized herb that is commonly used in the prominent and ever growing field of holistic medicine. Like mainly organic herbs, Wormwood has been known to help in the overall general function and cleanliness of many internal organs.

Legal status & potential side effects:

While Wormwood is openly bought and sold at markets both online and off, it is the active ingredients and natural oils that the herb contains that make it a potential dangerous product.

The key ingredient Thujone, which is a chemical similar to that of tetratetrahydocannibinol or THC that is active ingredient in the illegal substance marijuana, has been found to be unsafe by the FDA because of Section 801A in the Federal Food, Drug and Cosmetic Act of 1972 that bans the specific additive of thujone in any food product (alcohol being included).

This is mainly the reason the illegal status of the alcohol Absinthe that is still banned in the United States as well as many European countries (excluding the United Kingdom, Spain, Portugal, Andorra, Sweden, Denmark and the Austro-Hungarian Empire).

Is it All Hype?

However, the overall hype of Absinthe is characterized as being overplayed and over exaggerated. The psychoactive abilities of the alcohol are not as bad as previously thought and the addictive allegations (mainly due to the presence of the active ingredient Thujone that is present in the controlled substance marijuana) are far fetched and false.
Benefits of Wormwood
As long as the consumer who purchases the herb is only intending to use it for personal use and not for whole sale profit of the concentrated, distilled substance that is Absinthe, then the issues of legality are moot.

The complete list of ingredients found in the herb Wormwood are as follows:

(absinthol, azulene,s glycosides, flavonoids, thujyl, thujone, sesquiterpene lactones)

Because Wormwood contains such active and controversial ingredients, the potential side effects are subject to the individual. These side effects include:

  • Diarrhea (from the excessive production of bile and the secretion of the intestines, meaning to empty the bowels quickly)
    moderate to heavy sedation
  • It should not be taken over a longer period of time than four weeks or larger amounts in a single period because it can cause nausea, vomiting, insomnia, restlessness, vertigo, tremors and seizures.
  • It may be habit forming due to the active ingredients found in it and should not be taken over long periods of time
  • Those with pre-existing ulcers or gastritis conditions should not consume wormwood due to the irritable properties it contains which may exacerbate these conditions excessive use of the herb may result in nerve damage

As with any new health regiment, you should always consult a health care physician before proceeding with any introduction of a new or medicinal substance; it is best to consult a professional who has extensive knowledge or experience with medicinal herbs. If any adverse effects due occur after consuming Wormwood, the consumer should stop consumption immediately and consult a health care professional.

Typical Dosage/Usage & Preparation:

As stated above, Wormwood should not be taken for more than four weeks at a time and only the recommended dosage should be taken to avoid adverse side effects.

Wormwood can be consumed many different ways, but the most typical and effective way to get results is by drinking it in a tea or consuming it by tincture.

To Compose an Herbal Infusion of Wormwood Tea:

  • Take a 1/2 a full teaspoon (also 2.5 to 5 grams) worth of crushed herb
  • Add to 1 cup (also 250 ml) of boiling water
  • Let steep in boiling water for ten to fifteen minutes
  • (optional) Steep with peppermint or caraway or any other masking herb to the mix to help conceal the bitter flavor of the boiled Wormwood and also to achieve a more poignant form of health benefits (i.e. IBS, heartburn, etc.)
  • A total of three cups (750ml) of Wormwood tea may be consumed daily and should not exceed use longer than four weeks.

To effectively add a tincture:

  • Form a concentrated/distilled extract of the herb Wormwood
  • Add 10-20 drops of extract (1/8 teaspoon) to a 250 ml glass of water
  • Take at least ten to fifteen minutes before each meal (this is meant to help with stimulating a poor appetite)

Important: Do not exceed use of extract longer than four weeks and take no more than three times a day and take no more than one 250ml glass of diluted tincture before each meal.

The consumption of Wormwood by smoking has no effect what so ever and should not be used regularly as a sedative.

Product Cost & Market

Wormwood can be found both offline and online and is mostly commonly sold by noted herbalists or natural food shops in bulk. By buying in bulk, you have a better chance for saving per bundle. Also, concentrated tinctures can be purchased online or in food stores as well.

The going cost for bulk Wormwood, whether they be organic, dried, or mixed ranges from about $4 to $10 dollars and is most commonly sold in concentrated tinctures. Most are infused with pleasing flavors such as walnut or peppermint to mask the bitterness.

It may also be found in capsulated forms at any store that contains a generic vitamin aisle.
Wormwood is fairly inexpensive and can even be grown in a simple herb garden for an enthusiast and it is the best way to access fresh Wormwood during its optimal growing season which is mid-summer, specifically June to August when the herb is picked and dried.

To Grow Wormwood:

As with almost any herb, a shady area is idyllic. All seeds, roots should be sown by mid autumn (to achieve optimal ripeness of the seeds) and placed at least two feet apart to allow natural expansion of growth. Nothing else is required in caring for this herb, as it naturally grows wild in most parts of the U.S anyway and is meant to be a withstanding plant, most commonly used in professional landscaping.

Keep free of weeds and expect an explosion of growth to come mid May or early June.

Each plant should be gathered, and separated in July or August and dried in the traditional form of drying flowers by hanging from a clothesline or any suspended wire that has access to fresh air and sun.

To Process:

Before drying effectively, the upper green portion of the flower should be separated from the lower parts of the stems which will be discarded and eliminate any insect eaten or discolored leaves. Loosely bundle in groups of six that match in both size and length (this is important when packing the groups of stalks together) and fan out to allow the air to get to each individual stalk.

Hang on any wire or line with access to air on a day with plenty of sun and warmth, however hang in half shade so as not to tinder the leaves. If dried in direct sunlight, the aromatic properties of the Wormwood (which is the most prized part of collecting Wormwood) will be lost.

Proper Temperature

It is a general rule that all aromatic herbs should be dried in a temperate setting that does not exceed 70 to 75 degrees Fahrenheit.

If there is no available sun to dry the herb, use a covered shed or greenhouse that is properly ventilated to expel the moist, warm air. To substitute the warmth of the sun, a anthracite or coke stove may be used to heat the room, but take caution to keep all windows open for proper ventilation.

Finishing the Process

If the leaves are still crisp the stalks are not fully dried, hang over a stove, with enough distance between stove and herb to avoid it catching on fire, and they will quickly dry.

After the drying process is complete, it is crucial to store the dried herbs, (equal in length and size) in air tight boxes to avoid the absorption of moisture from the air (typically the herb is capable of absorbing back 12% of the moisture, ruining the batch).

From then you may enjoy you’re fresh Wormwood and either crush it down to make for tea or process further to use the extract in a tincture.

Overview

While the Greeks and Romans believed it a bitter substance that would aid only if one was bitten by a sea dragon, consumed a poisonous mushroom or seeking for your one true love, Wormwood is a fantastic herb that can be used to aid in several areas of health related issues. Mostly drunk in the form of a peppermint or caraway tea, it can help aid in digestion, clear the intestinal tract, aid in the relief of IBS, help prevent liver dysfunction, gallbladder function and as a mild sedative.

The herb contains the ingredients thujone and absinthol and should be taken with precaution. The use of Wormwood should not extend longer than the duration of four weeks and and no more than three cups of Wormwood tea should be consumed at one time.

Find an Expert

As always, it’s best to consult a health care professional or someone who has expert knowledge in the consumption of herbs as a means of holistic medicine. As with several herbs, Wormwood may have adverse side effects, such as diarrhea, nerve damage (with excessive use) and moderate to heavy sedation. If any of these side effects persist, you should stop consumption of the herb immediately.

Though most commonly associated with the French spirit, Absinthe (due to its active ingredient of absinthol) , Wormwood was most traditionally used in brewery’s instead of hops until the FDA deemed the presence of such ingredients like thujone to be ‘unsafe’ for public consumption.

It is available for whole sale purchase at most health food stores in the form of capsules and concentrated tinctures. It is also simple to grow Wormwood and is best harvested in May or June; early summer.

Conditions

Frequent Urination

Frequent Urination Condition

Frequent urination simply means urinating more often than usual. Its a symptom rather than a condition. Most people empty their bladders between four and eight times a day; frequent urination is therefore defined as voiding urine more often than eight times a day with the implication that this increased rate is not strictly volitional.

Frequent urination does not always signify an underlying health problem.

You may be drinking too much fluid, or possibly you need to modify your food and beverage intake: alcohol, caffeinated beverages such as coffee and tea and even some foods such as celery, watermelon and parsley are natural diuretics increasing the amount of urine you would normally excrete.

Female Urinary System.

Underlying Problems

But frequent urination is often a sign of an underlying medical pathology, most often a urinary tract infection or cystitis (an inflammation of the bladder) that can affect either sex although it most common in women.

Frequent urination can also be the first symptom of diabetes, both type 1 and type 2, as the body mobilizes the urinary system to rid itself of excess glucose.

Frequent urination is linked to prostate problems in men and to pregnancy and pelvic inflammatory disease in women. The symptom is also a common side effect of obesity and abdominal radiation treatments.Frequent Urination Symptoms

Even when frequent urination is not connected to an underlying pathology, it can be a disruptive and embarrassing condition. When you have to go, you have to go no matter what else is happening around you.

When frequent urination forces major changes in lifestyle habits or is accompanied by fever, pain, nausea and vomiting, increased or decreased appetite, genital discharge or changes in the appearance of the urine itself, it’s time to consult a physician about the condition.

Alternative Names

There are several different conditions which are closely associated with frequent urination:

Urgent Urination, Urinary Urgency

A sudden, compelling need to urinate linked to a burning sensation or pain, often a sign of an underlying urinary tract infection.

Urge Incontinence, Urinary Incontinence, Overactive Bladder Syndrome

A sudden, irresistible need to urinate due to bladder spasms. Symptoms include urinary frequency, urinary urgency, and sometimes leaking urine before you can get to a toilet.

Stress Incontinence

Involuntary urination that occurs during an activity such as coughing, sneezing or laughing, generally caused by an underlying anatomic weakness to the bladder.

Nocturia

Frequent urination at night involving waking up several times to use the toilet.

Polyuria

The production of excessive volumes of urine for an adult, over 2.5 liters in 24 hours.

Depending on the underlying cause of your urinary frequency, you may experience some of these symptoms as well.

Physiology

Urination is the process by which urine is eliminated from the body, a function which in healthy humans is partly under voluntary control.

Cellular metabolism generates nitrogenous waste products that must be eliminated from the bloodstream. These wastes are filtered out of the bloodstream by the kidneys. There are two kidneys in the body, each made up of microscopic structures called nephrons that act as filtering units removing most of the water, salt and waste from the blood that passes through them.

The resulting liquid waste product called urine is transported through anatomic structures called ureters to the bladder where it is stored. The anatomical structure of the ureters and bladder do not allow urine to back up towards the kidneys under most circumstances.

Bladder Muscles

The bladder has two sets of muscles controlling its opening. Only the external sphincter is under voluntary control. Both the internal sphincter and the smooth muscle in the wall of the bladder are under the control of the parasympathetic nervous system. As your bladder fills with urine, the smooth muscle stretches by means of small contractile waves to accommodate the extra volume of urine. When urination occurs, the bladder’s outer layer of muscle (called the detrusor) contracts to help push out urine.

Urine is excreted from the bladder through the urethra, a process called urination. The average adult bladder can hold between 300 and 500 cc of urine. Urine is sterile when it is excreted from the body: it contains fluid, salts and waste products, but it is free of bacteria, viruses and other pathogenic organisms.

Causes of Frequent Urination

Overactive Bladder

Overactive bladder is a condition associated with a sudden, irresistible urge to urinate, resulting from involuntary contractions of the musculature of the bladder wall.

Overactive bladder is particularly common among middle-aged and older adults, and some medical experts estimate that one out of ever 11 adults in the United States suffers from some form of it. Untreated overactive bladder can lead to an increased incidence of urinary tract infections and skin infections from the corrosive effects of urine on the delicate skin of the urogenital area. But treatment success rates are high: with behavioral modification techniques and medication, 80% of people are able to bring their symptoms under control.

Overactive bladder can be brought on by abnormalities of the nervous system such as spinal cord injuries, multiple sclerosis, strokes, Parkinson’s disease and diabetic neuropathy; by urinary tract infections; and by blockages to the urinary system such as those caused by kidney stones or an enlarged prostate. But in many cases, there is no underlying pathogenic cause to overactive bladder.

Medical History

Medical history plays an important role in diagnosis: urinary frequency, urinary urgency, stress incontinence and urinating more than three times a night are all suggestive of overactive bladder. A pelvic exam for women (to rule out pelvic inflammatory disease) and a prostate exam for men (to check for enlargement) are generally indicated. Ultrasonic measurement of the post-void residual (the amount of urine left in the bladder after urination) can further help determine whether symptoms are due to muscle spasms or some other cause.

If underlying pathology is ruled out then treatment for overactive bladder focuses on:

Improving the Tone of the Surrounding Pelvic Muscles

Doing Kegel exercises (also called pelvic floor exercises) for five minutes, two to three times a day, can markedly decrease incontinence in both women and men. Occasionally Kegel exercises are used in conjunction with biofeedback and electrical stimulation of the floor of the pelvis.

Behavioral Modification

Behavioral techniques called bladder training can teach you to resist the urge to urinate, gradually increasing the interval between trips to the toilet.

Peeing in public.

Medications

Several medications that block the effects of the neurotransmitter acetylcholine have proven successful in the treatment of overactive bladder. They share common side effects including dry mouth, constipation, blurred vision, and in the elderly, confusion.

  • Oxybutynin (Ditropan): Oxybutynin suppresses spasms in the smooth muscles of the bladder wall. Additionally it relaxes the detrusor.
  • Tolterodine (Detrol, Detrol LA): Tolterodine suppresses spasms in the smooth muscles of the bladder wall. It does not cause the mouth to dry out as much as Oxybutynin.
  • Solifenacin (VESIcare). Similar to Tolterodine, but with a longer half-life.
  • Tricyclic antidepressants such as imipramine (Tofranil) and doxepin (Sinequan, Adapin) have also been used to treat overactive bladder with some success. Their mechanism of action is not clear.

Natural Treatments

If you are suffering from the symptoms of overactive bladder, there are a number of remedies you can try at home without seeking medical attention. Regulate your fluid intake. If you smoke, stop. Consider eliminating coffee, tea and other caffeinated beverages and foods: caffeine is a known diuretic.
treating frequent urination
Foods such as chocolate, spicy cuisines, alcohol and carbonated drinks can also irritate the bladder. If you are even a few pounds overweight, consider going on a diet: middle-aged people tend to put on weight in their abdomen, and all that extra avoirdupois exerts extra pressure on your bladder.

Constipation, similarly, also exerts extra pressure on your bladder so consider increasing the amount of fiber in your diet if you suffer from it.

Some naturopathic doctors believe that overactive bladder is linked to food sensitivities, particularly to wheat and dairy products.

These foods, it’s speculated, cause a systemic inflammation that manifests, among other things, as an inflamed bladder. By cutting out one food group for a period of time and observing how your symptoms respond, you can pinpoint the dietary culprit.

Mineral Supplements

A number of botanicals and mineral supplements have also been used to treat overactive bladder with some success.

Pumpkin

Native Americans have used pumpkin seeds for centuries to improve bladder and prostate health. Pumpkin is also one of the few natural remedies to be tested in clinical trials: in one six-week study of postmenopausal women suffering from overactive bladder, almost 60% of participants showed marked improvement.

Magnesium

Clinical trials have also proven the efficacy of magnesium, particularly among patients suffering from Parkinson’s disease. It thought to control smooth muscle spasms.

Saw Palmetto

Palmetto is commonly used throughout Europe to treat the symptoms of benign enlarged prostate. Its precise mechanism of action is unclear but it has anti-inflammatory properties and is known to reduce the activity of enzymes linked to prostate problems. Clinical studies have proved that it reduces urinary frequency. But palmetto has some mild estrogenic effects; for that reason, women who are pregnant, breastfeeding, taking birth control pills or undergoing hormone therapy should avoid it.

Stress Incontinence

Stress incontinence is the involuntary loss of urine due to a sudden pressure on the abdominal muscles secondary to physical activities like coughing, sneezing or laughing.

While its symptoms and many non-invasive treatments are similar to those for overactive bladder, its underlying cause is quite different: it due to a weakening of the pelvic musculature which in men can occur following a prostatectomy and among women is a common aftermath to childbirth among women (exacerbated when estrogen levels decrease in the week before menstruation or following menopause.)

In addition to the treatments described under overactive bladder above, one non-surgical treatment that sometimes used for women suffering from stress incontinence is the insertion of a small ring-shaped medical device called a pessary into the vagina. The pessary reduces stress incontinence by compressing the urethra against the symphysis pubis bone. If a woman uses this treatment option, she must be carefully monitored by her physician to reduce the chance of contracting a vaginal or urinary tract infection.

Surgical treatment is only considered if other non-invasive treatments have failed and the exact anatomical site of the pelvic muscle weakness is known.

Nocturia

Nocturia is the medical term for frequent urination at night. It can be a symptomatic of a systemic disease process such as a kidney or bladder infection, diabetes or sleep apnea; in men, it is often the first sign of prostate enlargement. But even when its causes are relatively benign, nocturia can still be a difficult condition to live with because it interferes with sleep.

Interventions to try at home include minimizing all fluid intake but particularly caffeine and alcohol for at least three hours before bedtime, taking medications that have a diuretic effect earlier in the day, and avoiding strenuous exercise and potentially stressful interactions before sleep. You should see your physician if nighttime urination is accompanied by fever, pain or discomfort, or if your urinary frequency is not affected at all when you cut down on fluids before bedtime.

Medical History and Testing

Since nocturia is frequently a symptom of an underlying systemic pathology, when you visit your physician, he or she will try to rule these out by taking a thorough patient history, performing a physical exam, and ordering diagnostic tests such as urinalysis, urine culture, blood sugar and BUN/creatinine clearance.

Nocturia can be a symptom of benign prostate enlargement, urinary tract infection, kidney failure, congestive heart failure, obstructive sleep apnea or diabetes.

Urinary Tract Infections (UTI)

Urinary tract infections are the second most common type of infection, resulting in 8.3 million visits to doctors offices every year. UTIs are named differently according to the primary site of infection:

  • Urethritis is an infection of the urethra
  • Cystitis is an infection of the bladder
  • Pyelonephritis is a kidney infection

In addition to urinary symptoms like urinary frequency and urinary urgency, UTI symptoms can include low-grade fever, abdominal or back pain, and urine that appears cloudy and has an unusual or foul odor. With more serious infections that spread to the kidneys, symptoms may include a fever over 101 degrees Fahrenheit with chills and night sweats, nausea and vomiting and more severe pain in the abdomen or lower back or referred to the flank.

In a significant number of cases, UTIs are asymptomatic. Indeed among the elderly for whom UTIs are a huge concern, the only symptoms may be confusion, combativeness or other changes in mentation.

UTIs occur when bacteria contaminate the urethra opening and begin to multiply. The most common contaminant is Escherichia coli (E. coli), a bacteria which typically lives in the intestines and the most common source of infection in active individuals is fecal contamination following bowel movements. But any abnormality in the urinary tract that obstructs the free flow of urine a kidney stone, for example, or an external catheter can set the stage for infection.

Higher Risk Categories

Women are more prone to UTIs than men, possibly because their urethras are shorter and closer to the anus. Medical experts estimate that half of all women will experience a UTI at least once in their lifetime, and most of them more than once. Factors that increase a woman™s susceptibility to UTIs include sexual activity (because intercourse can irritate the urethra,) use of the diaphragm as a birth control device, and aging since the decrease in estrogen following menopause leads to more fragile urogenital tissues.

If the UTI involves mild discomfort but no fever, you can try to manage it at home. Your goal will be to flush the offending microorganisms by drinking lots and lots of water. Avoid drinking caffeinated beverages such as coffee and tea, alcohol and carbonated beverages as these will irritate your bladder. Since an ounce of prevention is worth a pound of cure, for the future remember to wipe from front to back after a bowel movement (rather than the other way around), to urinate as soon as possible after sexual intercourse and (for women) to avoid potentially irritating feminine hygiene products.

Cranberry Juice

For more than a century, cranberry juice has been used as a natural remedy for UTIs. Cranberries contain substances called proanthocyanins which seem to prevent bacteria from sticking to the walls of the urinary tract. Don’t use the highly sweetened cranberry juice you find in supermarkets for this purpose. Instead use unsweetened cranberry juice or cranberry extract tablets available from health food stores.

If you are running even a low-grade fever or your UTI is causing you significant discomfort, then you should opt to see a physician for treatment.

Definitive diagnosis will be made on the basis of a urinalysis done on a clean, mid-stream catch specimen of urine. Blood, pus and/or bacteria will be present in a urinalysis that’s positive for a UTI. Occasionally a urine culture may also be ordered to test for specific strains of bacterial infection. Other tests your physician may order if he or she thinks your infection may be more serious include blood cultures and a CBC.

Treatment Options

The first line of treatment for a simple UTI is antibiotics. Commonly used antibiotics include Amoxicillin (Amoxil, Trimox), Ciprofloxacin (Cipro), and Sulfamethoxazole-trimethoprim (Bactrim). Symptoms often respond to treatment within 24 hours, but it is important to complete the antibiotic regimen even if symptoms have disappeared otherwise the implicated bacteria may develop a resistance to that antibiotic.

Your doctor may also prescribe medication called Phenazopyridine hydrochloride (Pyridium) to control the burning sensation you experience upon urination. One side effect of Pyridium is that it turns your urine bright blue!

If your UTI has made you extremely sick or you are incapacitated in some way that makes your doctor think you will be unable to adhere to the antibiotic protocol (as sometimes happens with elderly patients), your doctor may recommend hospitalization so that antibiotics and fluids can be administered intravenously

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Conditions

Angina

Angina, also known as Angina Pectoris which means squeezing of the chest in Latin, is a symptom of ischemic heart disease. The chest discomfort, pressure and pain are caused by the coronary arteries delivering an inadequate amount of oxygen-rich blood to the heart. The two main causes of angina are artherosclerotic plaque buildup and coronary artery spasm. If left untreated, angina can result in total blockage of the arteries and cause a heart attack.

The risk of heart disease and heart attack increases with the number of risk factors you have and their severity. Some heart disease risk factors can develop within the first ten years of life. Risk factors include hypertension, coronary artery disease, high blood fats or cholesterol, family history of premature ischemic heart disease, smoking, high blood pressure, obesity and diabetes. Angina occurs more frequently in men than in women. The most frequent cause of angina is coronary artery disease. The risk factors you cannot control are family history, age and gender.

Four Different Types of Angina.

Stable Angina

Stable angina is chest pain or discomfort that usually occurs with stress or physical activity. It begins slowly and intensifies before going away but reoccurs with additional activity or stress. The pain usually lasts from one to 15 minutes and is relieved with medication or rest. The frequency and severity of the pain does not change much.

Symptoms of Stable Angina include pain that occurs behind or slightly to the left of the breastbone and a feeling of tightness, pressure, squeezing or crushing pain in the chest. Stable Angina can be treated with medication, angioplasty or stenting. Medications require no recovery time and are much less expensive than angioplasty and stenting.

People who take only medications to relieve their angina may not have quick chest pain relief, but if you choose to take medications to treat your angina, it’s important that you take them exactly as your doctor instructs you so that you get the maximum benefit from your medications.

Angioplasty and stenting may have earlier and better symptom relief, such as reduced chest pain but research has shown the chest pain relief was about the same between those who have angioplasty and stenting and those who only take medication after five years.

Unstable Angina

Unstable angina is chest pain that occurs suddenly and gets increasingly worse. It is the most serious form of angina and requires immediate medical attention. The chest pain lasts longer than 15 – 20 minutes, may occur along with a drop in blood pressure or significant shortness of breath, occurs without cause and responds poorly to nitroglycerin.

Calcium channel blockers are extremely effective in preventing the coronary spasms of variant angina. These drugs, along with nitrates, are the most common treatment. If you have unstable angina, you most likely will be admitted to the hospital and given medicines, including heparin, aspirin and other antiplatelet medicines.

Unstable angina requires close monitoring and testing. If you are at high risk for heart attack and chest pain continues after the above treatment, your doctor may decide to perform coronary catheterization and plan for possible angioplasty and stent placement to prevent a heart attack.

Variant Angina

Prinzmetal’s or variant angina is caused by spasm of one of the coronary arteries. It is usually the result of severe coronary atherosclerosis in at least one major vessel. The spasm normally occurs very close to the blockage. It mostly occurs spontaneously and unlike typical angina, it nearly always occurs when a person is at rest. It doesn’t occur with physical exertion or emotional stress.

Attacks can be very painful and usually occur between midnight and eight a.m. Treatment helps to control chest pain and prevent a heart attack. Nitroglycerin is frequently used to relieve an episode of pain. Nitrates, beta -blockers or calcium channel blockers may also be prescribed.
angina symptoms
The medication dosage can be gradually reduced after six to 12 months of treatment. In some cases surgery is used when blockages exist along with spasm.

Microvascular Angina

Microvascular angina is caused by inadequate blood flow through the tiny cardiac blood vessels. Microvascular angina symptoms include chest pain or discomfort, a crushing or burning sensation in the chest, and pain or numbness in the arms, shoulders or jaw.

Microvascular angina usually occurs during routine daily activities and times of mental stress. It may be more severe or last longer than other types of angina pain. Symptoms include shortness of breath, sleep problems, fatigue, and lack of energy.

Treatment for microvascular angina includes nitroglycerin, calcium channel blockers or beta blockers and lifestyle changes. Since microvascular angina is not caused by significant arterial blockages, it is harder to recognize and diagnose.

Diagnosis

Laboratory tests can help the physician identify angina and conditions that may contribute to its development.

Urinalysis may reveal underlying conditions such as diabetes mellitus or renal disease, both of which are associated with atherosclerosis.

A chest x-ray may show an enlarged heart or other signs of possible heart failure.

Blood tests may show elevated CPK (creatine phosphokinase) level. When heart tissue dies it causes the enzyme CPK to be released into the blood. Blood tests to check for inflammation, high cholesterol and glucose levels are also used to diagnose angina. Stress tests are commonly used to evaluate coronary artery disease.

EKG

During a stress test an electrocardiogram (ECG or EKG) is taken before, during and after exercise on a treadmill or stationary bicycle. Patients who are at risk for a coronary event with exercise are given a drug to increase the heart rate instead of exercising on the treadmill. A normal ECG could indicate a patient’s chest pain is caused by something other than a blocked coronary artery.

A coronary angiogram consists of injecting contrast material into the bloodstream and taking x-rays of the coronary arteries. This enables the physician to see malformations, blockages, and stenosis in the vessels. In variant angina, spasm of an artery may be induced during angiography and would help confirm a diagnosis of that form of angina.

Echocardiography is a procedure used to evaluate the valves, function, and size of the heart. This diagnostic test uses soundwaves to take a detailed picture of the heart. A nuclear heart scan shows the level of blood flow to the heart by providing moving pictures of the blood flowing through the heart and arteries.

Medication Side Effects

All medications used to treat angina have similar side effects which should be reported to your physician immediately if they worsen or persist. They include headache, dizziness, flushing and restlessness. Blurred vision, dry mouth, nausea, pale skin or rapid heartbeat are serious side effects that should be reported immediately.

If the medication is working you will experience headaches which can be treated with aspirin or non aspirin pain relieve unless they become severe. Rash, itching, swelling, severe dizziness or trouble breathing are signs of an allergic reaction to the medication and require immediate attention.

Natural Herbs can help control angina symptoms. The following herbs are the most commonly used to relieve the symptoms of angina.

Garlic

Garlic contains substances that discourage platelets from sticking together and helps prevent blood clots. It also lowers total cholesterol and triglycerides while increasing HDL, the good cholesterol. Include one clove of garlic in your daily diet or take 10 milligrams per day.

Ginkgo

Ginkgo’s antioxidant properties neutralize harmful molecules called free radicals. It increases blood supply to the extremities and makes heart cells more efficient. It keeps platelets from sticking together and has a tonic effect on blood vessels. Take 40 to 80 milligrams of capsules three times per day.

Hawthorne

This traditional European herb used in treating heart disease dilates coronary arteries, which increases blood supply to the heart. Hawthorne improves oxygenation and energy metabolism and helps decrease lactic acid which is the waste product of exertion that causes heart muscle pain.

Hawthorne contains antioxidant and anti-inflammatory properties that help strengthen artery walls and reduce cholesterol. Take 100 to 250 milligrams three times per day or drink one cup of tea three times per day. The tea can be made by simmering one teaspoon of dried berries or steeping one teaspoon of leaves and flowers in a cup of hot water for ten to 15 minutes.

Coleus

Coleus keeps platelets from sticking together, relaxes arterial muscles, and improves heart function. Take 50 milligrams two or three time per day. Use coleus carefully if you take blood pressure medication or if your blood pressure is already low. Coleus may also increase the effects of antihistamine drugs.

Khella

This herb improves exercise tolerance and normalizes heart rhythms in patients with angina. It also help to dilate coronary arteries. Take 250 to 300 milligrams per day. Reduce the dosage if you experience nausea, dizziness or decreased appetite.

Ginger

This aromatic herb works best if eaten fresh and on an empty stomach. It lowers cholesterol and keeps platelets from sticking together. Take 250 milligrams per day. At higher doses, ginger may cause upset stomach.

Lifestyle changes can also help to relieve and control the symptoms of angina. If heavy meals trigger angina then avoid large meals and rich foods that leave you feeling stuffed. Try to avoid situations that make you upset or stressed if that is what triggers your angina. Eating a healthy diet is also important and can help to prevent or reduce high blood pressure and cholesterol. Quitting smoking along with avoiding alcoholic beverages will also help to control angina and reduce the frequency of symptoms.

Heart Attack

Angina does increase your risk of a heart attack. It’s very important that you know how and when to seek medical attention. An emergency action plan is important and will improve the chances of surviving cardiac arrest.

The plan should include making sure you as well as your family members know the location of the nearest hospital that offers 24-hour emergency heart care. Make sure you know the signs and symptoms of a heart attack, how to reach emergency medical services in your community and how to use aspirin and nitroglycerin when needed.

If your chest pain becomes severe, lasts longer than a few minutes, or is not relieved by rest or medicine seek immediate medical care. It can be difficult to tell the difference between unstable angina and a heart attack. Both are emergency situations, so you should call for an ambulance right away.

Prognosis

A diagnosis of angina at least gives you some warning that you have coronary artery disease. Undiagnosed angina can lead to a heart attack or sudden cardiac death. If you are at high risk for a heart attack, you need to find out early so that you can get the best treatment right away. Getting the appropriate treatment combined with lifestyle changes can result in living a normal, full and healthy life.

Vitamins

β-Carotene

Beta Carotene

Beta  Carotene or B  Carotene

Beta carotene is a vitamin A precursor that is produced by many different species of plants. It belongs to a group of chemicals known as carotenes, which are themselves part of a larger chemical group called carotenoids. beta-carotene, sometimes written as b carotene, is also known as provitamin A. Vitamin A, which can be synthesized from its provitamin, may sometimes be called retinol.

Carotenes belong to a large group of chemicals known as carotenoids. Carotenoids are all strongly colored red, yellow and orange pigments. They are fat or lipid soluble and are found in many different types of fruits and vegetables. Carotenoids are also antioxidants.

Chemical Makeup

A carotene is a type of chemical that was first discovered in the 19th Century after being isolated from carrots. There are three types of carotene that can be used by the human body to produce Vitamin A: alpha, beta and gamma carotenes. Since they are not themselves vitamins, but can be converted into a vitamin, the carotenes are considered to be precursors or provitamins.
using beta carotene
The chemical that can be produced from the carotenes, vitamin A, is an essential nutrient that plays a role in vision and growth. A vitamin A deficiency can be seriously harmful, and may even lead to death, although it can be cured by eating a diet rich in fruits and vegetables, which contain high levels of beta-carotene.

Carotenes are produced by plants, but although they are necessary as vitamin precursors in animals, they must be obtained from food since animals cannot synthesize carotenes for themselves.

Animals can produce vitamin A, however, and it is therefore possible to get vitamin A directly from the diet rather than having to manufacture it from beta-carotene. Beta or b carotene is the most common form of carotene.

Chemistry

All carotenoids are based upon a chain of hydrocarbons. This is made up of small units of isoprene. In beta-carotene, there are eight isoprene units, which form beta cycles at either end. This means that the units on the ends of the molecule are twisted around into circles.

The exact molecular structure of beta-carotene was discovered in the early 1930s. This was the first time that the structure of any vitamin or vitamin precursor had been established.

The orange color of a carotenoid is produced by the long chain of isoprene units. This is because the hydrocarbon chain absorbs light in the blue and green ranges, but reflects back red and yellow light. Only the reflected light is seen by the observer. beta-carotenes are found in orange and yellow colored fruits and vegetables, and are responsible for the color of these foods.

There are also beta-carotenes present in many green vegetables and leaves, but the orange color of the beta-carotenes is hidden by the green color of the chlorophyll. The leaves of deciduous trees turn orange before they fall because the chlorophyll in them has been broken down, leaving only the color of the carotenes.

During the 1950s, scientists began to develop techniques for artificially synthesizing beta-carotene. This led to the production of synthetic beta-carotene supplements and food colorings.

B carotene and Vitamin A

beta-carotenes are converted by the body into vitamin A or retinol. beta-carotene is converted into retinol, which is necessary for the eyesight. Retinol is converted into retinoic acid, which is used for growth and cell division. The functions of beta-carotenes in the body are therefore the same as those of vitamin A, since beta-carotene is converted into vitamin A before being used.

Beta-carotene is usually converted into vitamin A by gradually breaking down the beta-carotene molecule from one end, but it can also be converted by splitting the molecule in two. The conversion takes place within the cells that make up the small intestine. An enzyme called beta-carotene dioxygenase carries out the process.

Once vitamin A has been produced, it needs to be stored until it is required. It is first converted into retinyl esters, and is then transported through the body in the lymphatic system and blood. The vitamin A that is produced from the breakdown of beta-carotene is mainly stored in the liver in the form of retinyl esters. Some retinyl esters are also stored in the kidneys, lungs and adipose fat tissue, but between 50 and 80 percent of stored vitamin A is found in the liver.

Function

Vitamin A is essential for vision. The body converts vitamin A or retinol, through an oxidization reaction, into retinal. This is combined with an opsin protein in order to produce a light sensitive molecule. When one of these molecules is hit by a photon of light, the retinal component changes its shape, setting off a sequence of events that will eventually lead to a signal being sent to the visual part of the brain through the optic nerve, where it will be decoded as vision. Retinal is responsible for the ability to detect light and therefore to see.

There are two different types of light sensitive cell in the eye, and they use different chemicals in which to see. Rhodopsin is present in the light receptors known as rods, whereas a different chemical called Iodopsin is used by the cone cells. Rods are most effective in dim light, while cones provide color vision. Both types of receptors depend upon the ability of retinal to react to light.

Vitamin A also performs some other functions in the body. It is used in the production of some glycoproteins, which are protein molecules to which carbohydrates have been attached. Vitamin A plays a crucial role in growth and bone development, reproduction and the maintenance of the skin and mucous membranes such as the lining of the mouth and nose.

These linings help to prevent infection by keeping out infectious agents from the digestive system, urinary tract and the respiratory system. The importance of vitamin A in the body is clear, since a deficiency of this vitamin can lead to abnormal development of the bones, reproductive disorders, a condition called xerophthalmia that caused the cornea of the eye to become dry, and even to death.

Deficiency

Most people will consume an adequate amount of beta-carotenes in their normal diet, but it is possible to suffer from a vitamin A deficiency when a poor diet does not provide enough vitamin A or the carotenes fro which it can be manufactured. A diet that contains low levels of beta-carotenes will not be harmful as long as enough vitamin A is being consumed in other food. A diet without enough vitamin A or beta-carotene will be harmful. If there is a deficiency of vitamin A, due to malnutrition or illness, it can be cured by eating beta-carotene rich foods.

The earliest symptoms of a vitamin A deficiency are visual problems in low light situations, dry hair and skin, fingernails that break easily and a lowered resistance to infection. The more serious signs of a vitamin A deficiency are anemia, abnormal bone development, and permanent damage to the eyes.

The retina may be injured badly enough to cause blindness. Even when there are no vitamin A deficiency symptoms, a person who is not getting enough vitamin A could suffer from an increased risk of developing diarrheal and respiratory infections and a decreased growth rate and bone development. Fertility can also be reduced.

Health Problems with Deficiency

A vitamin A deficiency can be very serious. It is rare in the US, where most people consume more than enough beta-carotene and vitamin A in their diet.

However, a deficiency in vitamin A is the most common cause of preventable blindness in children worldwide, and it affects people in more than half of the countries in the world. Low income families in Southeast Asia and Africa are most likely to be affected. It is the young children and pregnant women within these families who are most likely to suffer from vitamin A deficiencies.
beta carotene
Vitamin A is required at higher levels during pregnancy, and children have smaller stores of vitamin A in their livers than adults. An adult can have enough vitamin A in their liver to last for an entire year, but a child’s supply can only last for a few weeks at most.

During Pregnancy

During pregnancy, the highest risk of developing a vitamin A deficiency occurs during the third trimester, when both baby and mother require large amounts of vitamin A. If the mother is not receiving enough vitamin A during this period, she will suffer from night blindness, and may experience other symptoms. \

She may also have a higher risk of maternal mortality. It is not recommended for women who have a good, balanced diet to take vitamin A or beta-carotene supplements, however, since they are not necessary. Vitamin A supplements could even increase the chances of birth defects in the baby.

Deficiency in Children

Children who are not obtaining enough vitamin A are at risk of blindness and other visual impairments, and they are also more likely to catch serious diseases such as measles, or to suffer from diseases that can cause diarrhea. These illnesses can be fatal. A lack of vitamin A can also cause growth problems and defects in the development of the skeleton.

According to the World Health Organization (WHO) it is estimated that there are 250 million children of preschool age who are suffering from a vitamin A deficiency, and that between 250,000 and 500,000 of these children are made blind because of this deficiency every year. Half of the children who go blind in this way will die within the next year.

It is possible to die from a vitamin A deficiency, and according to the World Health Organization (WHO), it is possible to significantly decrease mortality rates by ensuring an adequate supply of vitamin A.

Cases in the US

In the US, cases of vitamin A deficiency are most likely to occur in patients who are elderly or who are suffering from chronic illnesses that can reduce the absorption of vitamin A and carotenes from the intestine. Patients who have inflammatory bowel disorder (IBD), pancreatic insufficiency or cystic fibrosis have an increased risk of vitamin A deficiency.

Vegans and people who suffer from alcoholism are also more likely to have a deficiency, due to decreased ingestion and absorption of vitamin A. Some cases of malnutrition do occur in the US, but these are more common overseas.

It is possible to treat a vitamin A deficiency by eating foods that contain beta-carotene or vitamin A, or by taking supplements of one of these chemicals.

If the diet contains too much beta-carotene, it can lead to the skin turning a yellowish color. It will not, however, cause an excess of vitamin A in the body. Some of the vitamin A that is produced but which is not currently needed will be stored in the liver, where it can remain for several years. Some will be stored in the fat tissue of the body. If there is a lot of beta-carotene in the diet, then it will not all be converted into vitamin A. An excess of vitamin A in the body would be harmful.

Traditional Beliefs

It is often said that carrots can help people to see in the dark. Since one of the symptoms of a vitamin A deficiency is night blindness, this belief clearly has some foundation in fact. Although eating carrots cannot enhance night vision above normal abilities it can prevent it from deteriorating by providing the precursor for vitamin A production.

Antioxidant

beta-carotene is an antioxidant. Antioxidants are chemicals that can react with free radicals, which are highly reactive, charged molecules. Free radicals are produced by the body during respiration or energy production and can cause damage that in involved in the ageing process and cancer. It may be possible for antioxidants in food to protect the body from this sort of damage, but there is no definitive scientific proof that eating foods containing high levels of antioxidants can actually help to protect the body.

Medicinal Uses

beta-carotene has been approved by the US Food and Drug Administration (FDA) as a treatment for erythropoietin protoporphyria. This is an inherited condition that is very rare. It causes problems in the metabolism of the chemical porphyrin-heme. This can lead to photosensitivity, with the skin reacting painfully to light, dysfunction of the liver, and production of gallstones. Patients are treated with an over the counter beta-carotene supplement, and may also need to take antihistamines.

Consuming beta-carotene and other carotenoids can help to prevent a vitamin A deficiency, but a diet that is rich in carotenoids is not necessary as long as there is plenty of vitamin A in the diet. There is therefore no recommended intake of carotenoids according to the Institute of Medicine’s Food and Nutrition Board.

The American Heart Association, among other health groups such as the International Agency for Research on Cancer (part of the World Health Organization) advise that people should obtain beta-carotene from a diet that is high in fruits and vegetables rather than by taking dietary supplements.

Some of the scientific research that has been conducted on beta-carotene treatment has not yet produced clear results. These treatments have not yet been proven to be successful, but neither have they been proven unsuccessful.

Potential Uses

These potential uses for beta-carotene are as treatments for cataract prevention, reducing the adverse side effects of chemotherapy, treating chronic obstructive pulmonary disease (COPD), improving cognition and memory, preventing asthma attacks that are induced by physical activity, enhancing the immune system, promoting remission in patients with oral leukoplakia, preventing and slowing the progression of osteoarthritis, treating polymorphous light eruption (PLE), reducing the risk of sunburn and UV induced erythema, and reducing complications during pregnancy. Further research may clarify the effect of beta-carotene on these conditions.

beta-carotene has also been tested as a treatment for a number of other conditions for which it was not found to be helpful.

Potential Side Effects

There was even some evidence that it could be harmful when used in patients with these conditions, particularly if beat carotene was a replacement for other more beneficial therapies. beta-carotene was not found to be effective for the prevention or treatment of Alzhemier’s disease or abdominal aortic aneurysms (AAAs), preventing the development of new moles on the skin, preventing cancer or cardiovascular disease, eradicating the bacteria that can cause stomach ulcers (Helicobacteria pylori), preventing or slowing macular degeneration, preventing stroke, or reducing injuries following surgery.

Taking supplements of beta-carotene was also found to have no effect on overall mortality rates. There is some evidence that beta-carotene may be harmful in patients who have undergone angioplasty.

Sources of Beta-Carotene

beta-carotene occurs naturally in many plants. It is found in green vegetables and fruit and vegetables that are orange or yellow. Spinach, broccoli, carrots, red peppers, nectarines, melons and mangoes are all good sources of beta-carotenes.

A diet that includes five portions of fruit and vegetables every day will provide between 6 and 8 milligrams of beta-carotene per day. A healthy body can maintain adequate levels of vitamin A with just 1800 micrograms of beta-carotene, therefore it is rare for a diet to be deficient in carotenes. There is no recommended daily allowance (RDA) for beta-carotenes, due to a lack of evidence on its importance, but the RDA for vitamin A is 0.9 milligrams per day for an adult man and 0.7 milligrams a day for an adult woman. Pregnant women and those who are breastfeeding require a higher daily intake.

Vitamin A can also be consumed directly, rather than as its precursor, beta-carotene. Egg yolks, dairy products and fish oils all contain high levels of vitamin A. Liver is also rich in this vitamin, and in fact, the liver of the polar bear contains such large amounts of vitamin A that it is poisonous to humans.

Supplements

beta-carotene is available as a dietary supplement. It can be manufactured synthetically or derived from fungi, algae or palm oil. Supplements of beta-carotene can be taken in a number of different forms, including gelatin capsules, tablets and chewable tablets.

There is some scientific evidence that consuming too much beta-carotene in the form of supplements may be harmful. A study found that there was an increased risk of developing lung cancer when people who were exposed to other risk factors for the disease, such as smoking or working in an environment where they were exposed to asbestos, took beta-carotene supplements.

There is no evidence of what the effect may be on non-smokers and people who are not already at an elevated risk of lung cancer, but it is possible that taking supplements of beta-carotene could be harmful. No similar effect has been detected when beta-carotene is eaten in food.

This means that it is important, when taking beta-carotene supplements, to avoid consuming too much beta-carotene. The UK Food Standards Agency advises against exceeding a dose of 7 milligrams of beta-carotene a day. Doctors may recommend taking a higher dose than this in some cases, but this is only when there is a serious deficiency that needs to be corrected. Anyone who is a smoker or who has been exposed to asbestos should avoid taking supplements of beta-carotene.

Absorbing Beta-Carotene

In order to absorb beta-carotene, the body must use some of the fat that has been eaten. This means that when beta-carotene is taken as a supplement, it will require some dietary fat in order to be absorbed by the body. No difference has been found in the absorption rate between individuals consuming a low fat or a high fat diet, however, since the amount of fat that is required is very low.

In order to absorb beta-carotene, the body must use some of the fat that has been eaten. This means that when beta-carotene is taken as a supplement, it will require some dietary fat in order to be absorbed by the body. No difference has been found in the absorption rate between individuals consuming a low fat or a high fat diet, however, since the amount of fat that is required is very low.

Elevated levels of vitamin A in the body can be harmful, causing problems with the bones that may lead to an increased risk of experiencing fractures in old age. Although beta-carotene is converted into vitamin A it does not pose a similar risk. The body is not efficient enough at turning beta-carotenes into vitamin A for a high intake of beta-carotenes to cause high enough levels of vitamin A to harm the body.

Food Coloring

In addition to being manufactured as a dietary supplement, beta-carotenes are produced and used as colorings in food products.

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